The prevalence of bone and joint diseases, which includes aging, infection, developmental and immune disorders, and other conditions, poses serious challenges to public health systems and society as a whole. The lack of understanding of their biology makes it difficult to develop diagnostic tools and effective therapeutic strategies. Over the past few decades, a number of orthopedic specialties have seen exponential growth in technology related to mechanisms, diagnosis and treatment. In order to provide new therapeutic options, a clear understanding of the mechanisms underlying the onset and progression of bone and joint diseases is required. Furthermore, a better understanding of the underlying molecular, cellular and system mechanisms of bone and joint function will be critical in the future classification of bone and joint diseases.
Current technological and methodological advances in bone and joint disease research are generating new insights that go beyond established hypotheses. Pathophysiological mechanisms, diagnosis and therapeutic treatments of bone and joint diseases have been significantly enhanced using omics technologies, nanomaterials, tissue engineering, artificial intelligence, gene editing technologies, and so on.
In this Research Topic, we hope to advance biological mechanisms in various bone and joint diseases, collect clinically feasible therapeutic solutions for improving patient outcomes and facilitating clinical adoption by encouraging researchers to discuss the latest developments in the diagnosis and treatment of bone and joint diseases. We welcome Original Research articles and Reviews work on potential subtopics including, but not limited to, the following:
• Cellular and molecular biological mechanisms associated with bone and joint diseases;
• Novel molecule diagnosis and drug therapy intervention approaches that improve the function of bone and joint systems;
• Mechanism and treatment of interactions between bone and joint diseases and other related systems, such as the endocrine system, digestive system, circulatory system, nervous system, and so on;
• Novel technologies in the mechanism, diagnosis and treatment of bone and joint diseases, including artificial intelligence, tissue engineering, stem cell and regenerative medicine, gene editing and omics technologies, and so on.
The prevalence of bone and joint diseases, which includes aging, infection, developmental and immune disorders, and other conditions, poses serious challenges to public health systems and society as a whole. The lack of understanding of their biology makes it difficult to develop diagnostic tools and effective therapeutic strategies. Over the past few decades, a number of orthopedic specialties have seen exponential growth in technology related to mechanisms, diagnosis and treatment. In order to provide new therapeutic options, a clear understanding of the mechanisms underlying the onset and progression of bone and joint diseases is required. Furthermore, a better understanding of the underlying molecular, cellular and system mechanisms of bone and joint function will be critical in the future classification of bone and joint diseases.
Current technological and methodological advances in bone and joint disease research are generating new insights that go beyond established hypotheses. Pathophysiological mechanisms, diagnosis and therapeutic treatments of bone and joint diseases have been significantly enhanced using omics technologies, nanomaterials, tissue engineering, artificial intelligence, gene editing technologies, and so on.
In this Research Topic, we hope to advance biological mechanisms in various bone and joint diseases, collect clinically feasible therapeutic solutions for improving patient outcomes and facilitating clinical adoption by encouraging researchers to discuss the latest developments in the diagnosis and treatment of bone and joint diseases. We welcome Original Research articles and Reviews work on potential subtopics including, but not limited to, the following:
• Cellular and molecular biological mechanisms associated with bone and joint diseases;
• Novel molecule diagnosis and drug therapy intervention approaches that improve the function of bone and joint systems;
• Mechanism and treatment of interactions between bone and joint diseases and other related systems, such as the endocrine system, digestive system, circulatory system, nervous system, and so on;
• Novel technologies in the mechanism, diagnosis and treatment of bone and joint diseases, including artificial intelligence, tissue engineering, stem cell and regenerative medicine, gene editing and omics technologies, and so on.