The optimal method of administering enteral nutrition in critically ill patients is unknown. Continuous enteral feeding is the most common practice worldwide, although unphysiological. In healthy young individuals, muscle protein synthetic response is stimulated 45-90 minutes after an oral bolus of protein, continues for about 90 minutes, then rapidly returns to baseline. Moreover, continuous tube feeding abolishes the entero-hormonal response. Intermittent feeding could prove superior to continuous feeding: in fact, it can stimulate muscular protein synthesis, and the inherent fasting periods may be protective through enhanced autophagy and ketogenesis.
From 27th-29th September 2022,
Società Italiana di Nutrizione Clinica e Metabolismo (SINuC) (The Italian Society of Clinical Nutrition and Metabolism) held the
5th SINuC National Congress in Lecce, Italy. The congress aimed to bring together clinicians and researchers in celebrating new developments in the areas of clinical nutrition and metabolism.
The proposed Research Topic therefore aims to stimulate research in this respect in order to implement new and potentially more effective feeding modalities during critical illness. We will collate contributions and presentations from the congress but also article submissions from non-attending authors. Submission of high-quality original research and review articles dealing with the optimal nutrition modality for critically ill patients are welcome.
The optimal method of administering enteral nutrition in critically ill patients is unknown. Continuous enteral feeding is the most common practice worldwide, although unphysiological. In healthy young individuals, muscle protein synthetic response is stimulated 45-90 minutes after an oral bolus of protein, continues for about 90 minutes, then rapidly returns to baseline. Moreover, continuous tube feeding abolishes the entero-hormonal response. Intermittent feeding could prove superior to continuous feeding: in fact, it can stimulate muscular protein synthesis, and the inherent fasting periods may be protective through enhanced autophagy and ketogenesis.
From 27th-29th September 2022,
Società Italiana di Nutrizione Clinica e Metabolismo (SINuC) (The Italian Society of Clinical Nutrition and Metabolism) held the
5th SINuC National Congress in Lecce, Italy. The congress aimed to bring together clinicians and researchers in celebrating new developments in the areas of clinical nutrition and metabolism.
The proposed Research Topic therefore aims to stimulate research in this respect in order to implement new and potentially more effective feeding modalities during critical illness. We will collate contributions and presentations from the congress but also article submissions from non-attending authors. Submission of high-quality original research and review articles dealing with the optimal nutrition modality for critically ill patients are welcome.