Obesity has become a global concern that threatens human lives and welfare. With its complexity and chronic nature, obesity can pose diverse consequences as a potent risk factor for metabolic syndrome (e.g., diabetes, cardiovascular diseases, fatty liver disease) and other direct effects like sleep apnea, asthma, osteoarthritis, and many more. Although the principal causes of obesity involve diets, behaviors, and lifestyles, many studies have proved that significant alterations at the cellular and molecular levels are substantially associated with the disease incidence and arise during the disease progression.
It is conceivable that many biological pathways and biomarkers are triggered and expressed during the incidence and progress of obesity. With available potent cell lines and advanced tools in molecular biology, we can elucidate the molecular mechanisms underlying obesity and its interplay with other diseases. However, additional updates in obesity-associated mutations have yet been essential to comprehend the molecular regulation of the disease. The molecular cross-talks between obesity and other less common comorbidities like infertility, aging, infectious diseases, and cancers are also rarely known.
We offer a platform for discussion, exchange, and updating our knowledge about the molecular mechanisms underlying obesity and its correlation with other comorbidities. Any studies implementing state of the art in molecular biology to unveil such molecular mechanisms are welcome.
• Biological pathways and biomarkers involved in obesity and its interplay with other diseases
• Organoid model and lab-on-chip for studying obesity and its comorbidities
• Unveiling mutation and mutagenesis in obesity and its comorbidities
• Implementing ‘omics’ approaches and bioinformatics to elucidate the complexity in obesity and its comorbidities
• Proposing/proving molecular mechanisms-based therapeutic strategies to regulate obesity and its associated illnesses
Obesity has become a global concern that threatens human lives and welfare. With its complexity and chronic nature, obesity can pose diverse consequences as a potent risk factor for metabolic syndrome (e.g., diabetes, cardiovascular diseases, fatty liver disease) and other direct effects like sleep apnea, asthma, osteoarthritis, and many more. Although the principal causes of obesity involve diets, behaviors, and lifestyles, many studies have proved that significant alterations at the cellular and molecular levels are substantially associated with the disease incidence and arise during the disease progression.
It is conceivable that many biological pathways and biomarkers are triggered and expressed during the incidence and progress of obesity. With available potent cell lines and advanced tools in molecular biology, we can elucidate the molecular mechanisms underlying obesity and its interplay with other diseases. However, additional updates in obesity-associated mutations have yet been essential to comprehend the molecular regulation of the disease. The molecular cross-talks between obesity and other less common comorbidities like infertility, aging, infectious diseases, and cancers are also rarely known.
We offer a platform for discussion, exchange, and updating our knowledge about the molecular mechanisms underlying obesity and its correlation with other comorbidities. Any studies implementing state of the art in molecular biology to unveil such molecular mechanisms are welcome.
• Biological pathways and biomarkers involved in obesity and its interplay with other diseases
• Organoid model and lab-on-chip for studying obesity and its comorbidities
• Unveiling mutation and mutagenesis in obesity and its comorbidities
• Implementing ‘omics’ approaches and bioinformatics to elucidate the complexity in obesity and its comorbidities
• Proposing/proving molecular mechanisms-based therapeutic strategies to regulate obesity and its associated illnesses
