Molecular Mechanisms and Pathways in Cerebellar Function

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Editorial

28 July 2023

Editorial: Molecular mechanisms and pathways in cerebellar function

Catarina Osório

,

Alanna J. Watt

and

Lilian Kisiswa

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1 citations

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Catarina Osorio

Erasmus Medical Center

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The cerebellum, also known as “little brain”, regulates voluntary movements and coordination as well as higher cognitive and emotional functions. Hence, disruption of its circuitry is often the central cause of major brain disorders, including ataxia, autism spectrum disorders, and schizophrenia. The molecular processes involved in the formation and maintenance of the cerebellum are of great importance to deciphering the developmental and functional consequences of disrupting these processes.

The goal of this Research Topic is to highlight the latest findings on key molecules and pathways involved in cerebellar development, maturation, and function. In addition, we welcome studies focused on cerebellar dysfunction and the mechanisms involved. We highly encourage research merging molecular/cellular studies with systems neurosciences. Understanding the molecular and cellular mechanisms involved in cerebellar maturation and degeneration will enable us to explore novel therapeutic targets for severe brain disorders.

In this Research Topic, we encourage the submission of original research, methods, perspectives, and reviews, that explore the molecular mechanisms underlying cerebellar anatomy and function.

We particularly welcome the submission of articles on the following sub-topics:

- molecular and cellular mechanisms contributing to cerebellar development and maturation
- signaling pathways underlying cerebellar plasticity and function
- key molecules driving cerebellar dysfunction

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Catarina Osorio

Erasmus Medical Center

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Published In

Frontiers in Molecular Neuroscience

Brain Disease Mechanisms, Molecular Signalling and Pathways

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