The study of ion channels and transporters in cancer represents an emerging field in the biomedical research landscape. These proteins contribute to a variety of processes such as cancer cell proliferation, migration, invasion, and tumor vascularization leading to cancer progression and metastasis. Thus, targeting ion channels and transporters may represent a promising target for cancer therapy.
A broad range of compounds acting on ion channels and transporters have been revealed as promising tools to be used to treat cancer. The antitumor features of these compounds are enhanced when different therapeutic approaches are considered, for instance, by its combination with antineoplastic drugs, immunotherapy, or other molecules targeting essential processes in cancer development including metabolic pathways. This research topic aims to showcase the latest research regarding the relevance of ion channels and transporters in human tumors, giving special emphasis on their potential use in the clinical setting as biomarkers and targets for therapy.
With this Research Topic, we welcome original research and review articles, including effects and mechanisms of modulating ion channels and transporters in the treatment of human cancer. Topics include, but are not limited to, the following:
- Expression and role of ion channels and transporters in solid and blood cancer
- The role of ion channels and transporters in tumor drug resistance
- Ion channels and transporters as new targets for promising therapeutic approaches in cancer
- Ion channels and transporters as cancer biomarkers
The study of ion channels and transporters in cancer represents an emerging field in the biomedical research landscape. These proteins contribute to a variety of processes such as cancer cell proliferation, migration, invasion, and tumor vascularization leading to cancer progression and metastasis. Thus, targeting ion channels and transporters may represent a promising target for cancer therapy.
A broad range of compounds acting on ion channels and transporters have been revealed as promising tools to be used to treat cancer. The antitumor features of these compounds are enhanced when different therapeutic approaches are considered, for instance, by its combination with antineoplastic drugs, immunotherapy, or other molecules targeting essential processes in cancer development including metabolic pathways. This research topic aims to showcase the latest research regarding the relevance of ion channels and transporters in human tumors, giving special emphasis on their potential use in the clinical setting as biomarkers and targets for therapy.
With this Research Topic, we welcome original research and review articles, including effects and mechanisms of modulating ion channels and transporters in the treatment of human cancer. Topics include, but are not limited to, the following:
- Expression and role of ion channels and transporters in solid and blood cancer
- The role of ion channels and transporters in tumor drug resistance
- Ion channels and transporters as new targets for promising therapeutic approaches in cancer
- Ion channels and transporters as cancer biomarkers
