The genus Staphylococcus represents bacterial species capable of colonizing humans and responsible for a range of infections. These include skin and soft tissue infections as well as invasive infections of the bloodstream and various internal body sites. The main focus of research on the genus Staphylococcus has been for decades dedicated to a primary pathogen of humans - S. aureus and its interactions with the host. These interactions involve a wide range of human and bacterial factors. These may differ between various clinical isolates. One advantage of understanding their role is the identification of inhibitors effective in preventing life-threatening complications. A number of these anti-virulence agents have been reported in recent years and could become replacement therapies for targeting resistant bacteria in the future. The purpose of this Research Topic is to collect and discuss the most recent advances that concern phenomena related to Staphylococcus ssp. and its interactions with the host:
• Gene expression in the bacteria and the host during the immune response
• Inflammatory response
• Autophagy
• Biofilm formation
• New drugs/therapies and pharmacodynamics
Authors that recently published on these topics are welcome to submit Perspectives, Case Reports, Mini-reviews, and Opinions.
The genus Staphylococcus represents bacterial species capable of colonizing humans and responsible for a range of infections. These include skin and soft tissue infections as well as invasive infections of the bloodstream and various internal body sites. The main focus of research on the genus Staphylococcus has been for decades dedicated to a primary pathogen of humans - S. aureus and its interactions with the host. These interactions involve a wide range of human and bacterial factors. These may differ between various clinical isolates. One advantage of understanding their role is the identification of inhibitors effective in preventing life-threatening complications. A number of these anti-virulence agents have been reported in recent years and could become replacement therapies for targeting resistant bacteria in the future. The purpose of this Research Topic is to collect and discuss the most recent advances that concern phenomena related to Staphylococcus ssp. and its interactions with the host:
• Gene expression in the bacteria and the host during the immune response
• Inflammatory response
• Autophagy
• Biofilm formation
• New drugs/therapies and pharmacodynamics
Authors that recently published on these topics are welcome to submit Perspectives, Case Reports, Mini-reviews, and Opinions.