Defined as a clinical condition with concomitant heart and kidney disease, cardiorenal disease presents an urgent global issue, that has embarked decades of innovation and multidisciplinary research for its treatment and management, amongst the cardiovascular and nephrology research communities. Affected population groups are expected to increase over the years, ultimately impacting public health and healthcare utilization. Recent findings have proposed a 5-subtype classification system to allow for earlier detection and management of cardiorenal disease, though this is yet to be applied in conventional practice.
The cardiorenal nexus encompasses a bi-directional relationship between the heart and the kidneys; any acute or chronic dysfunction of either will subsequently result in a dysfunction of the other. As prognosis of these interlinked conditions are significantly worsened due to this pathophysiological relationship, pharmacological management in at-risk patients, such as the elderly, may also be compromised. Therefore, further research to better understand the pathophysiology of the cardiorenal nexus is essential to optimize the management of cardiorenal disease. As a result of this pathophysiological relationship, treatment of cardiorenal disease remains complex; increased interest and findings over the years reveal a multidisciplinary, collaborative approach, is optimal for the management of cardiorenal disease.
Frontiers in Cardiovascular Medicine have organised a Research Topic around cardiorenal disease. Led by a team of experts in the field, this Research Topic will accept manuscripts within this area of research, with the aim of providing the reader with a comprehensive overview on the latest discoveries and findings, analysis of previously published data, on the pathophysiology and management of cardiorenal disease.
Sub-topics include, but are not limited to:
1) Epidemiology of cardiorenal disease.
2) Prognosis of cardiorenal disease and stratification of prognostic risk.
3) Pathophysiological mechanisms of the cardiorenal nexus.
4) Novel diagnostic approaches for the early detection of cardiorenal disease.
5) Novel therapeutic interventions to improve outcomes in patients with cardiorenal disease.
Defined as a clinical condition with concomitant heart and kidney disease, cardiorenal disease presents an urgent global issue, that has embarked decades of innovation and multidisciplinary research for its treatment and management, amongst the cardiovascular and nephrology research communities. Affected population groups are expected to increase over the years, ultimately impacting public health and healthcare utilization. Recent findings have proposed a 5-subtype classification system to allow for earlier detection and management of cardiorenal disease, though this is yet to be applied in conventional practice.
The cardiorenal nexus encompasses a bi-directional relationship between the heart and the kidneys; any acute or chronic dysfunction of either will subsequently result in a dysfunction of the other. As prognosis of these interlinked conditions are significantly worsened due to this pathophysiological relationship, pharmacological management in at-risk patients, such as the elderly, may also be compromised. Therefore, further research to better understand the pathophysiology of the cardiorenal nexus is essential to optimize the management of cardiorenal disease. As a result of this pathophysiological relationship, treatment of cardiorenal disease remains complex; increased interest and findings over the years reveal a multidisciplinary, collaborative approach, is optimal for the management of cardiorenal disease.
Frontiers in Cardiovascular Medicine have organised a Research Topic around cardiorenal disease. Led by a team of experts in the field, this Research Topic will accept manuscripts within this area of research, with the aim of providing the reader with a comprehensive overview on the latest discoveries and findings, analysis of previously published data, on the pathophysiology and management of cardiorenal disease.
Sub-topics include, but are not limited to:
1) Epidemiology of cardiorenal disease.
2) Prognosis of cardiorenal disease and stratification of prognostic risk.
3) Pathophysiological mechanisms of the cardiorenal nexus.
4) Novel diagnostic approaches for the early detection of cardiorenal disease.
5) Novel therapeutic interventions to improve outcomes in patients with cardiorenal disease.