Arthritis which has been represented by osteoarthritis and rheumatoid arthritis has become the most common joint disease in developing countries. They belong to inflammatory joint diseases caused by multiple factors which can affect many joints, such as hands, feet, hips, and knees. The typical symptoms of arthritis are chronic pain and deformity, affecting 340 million and 13 million people worldwide, respectively. By 2030, about 35% of the world's population will suffer from osteoarthritis. Rheumatoid arthritis has a high disability rate, which seriously threatens people's health and subsequently affects their quality of life. The high prevalence of arthritis causes severe economic burdens on individuals and society. An effective treatment plan is particularly important for patients with arthritis to improve their life quality.
The current treatment of arthritis includes medications, physical therapy, and surgical intervention, which are aimed at alleviating symptoms and reducing joint damage and disability. At present, most sports and surgical treatments mainly control pain symptoms and do not inhibit pathological changes. Clinically, traditional Chinese medicine such as Chinese herbal medicine and acupuncture, play an important role in arthritis treatment through delaying the pathology progression or alleviating pain. Traditional Chinese medicine mainly regulates the development of arthritis based on metabolic networks, transcriptional regulatory networks, and protein interaction networks. Furthermore, epigenetic alteration is also a common mechanism for the treatment of arthritis with traditional Chinese medicine. This special issue will focus on the treatment of osteoarthritis and rheumatoid arthritis with traditional Chinese medicine, reveal its molecular mechanism and provide a theoretical basis for further improving the drug efficacy in arthritis treatment.
This research topic mainly gathers the original researches and reviews that report arthritis treatment (osteoarthritis or rheumatic arthritis) with traditional Chinese medicine such as Chinese herbal medicine or acupuncture, or how the different factors such as kidney deficiency, blood stasis, and cold dampness influence the pathogenesis of arthritis.
Topics may include but are not limited to the following:
-The effect and mechanism of traditional Chinese herbal medicine on the treatment of arthritis through proteomics analysis, transcriptomics analysis, metabolomics analysis, and epigenetics analysis.
-Revealing the molecular mechanism of different factors (kidney deficiency, blood stasis, cold dampness) that cause arthritis through proteomics analysis, transcriptomics analysis, metabolomics analysis, and epigenetics analysis.
-The effect and mechanism of acupuncture on the treatment of arthritis through proteomics analysis, transcriptomics analysis, metabolomics analysis, and epigenetics analysis.
This special publication should be scientific, innovative, and published online after fully open, fair, and strict peer review. Once the article is online, it can be quoted.
Arthritis which has been represented by osteoarthritis and rheumatoid arthritis has become the most common joint disease in developing countries. They belong to inflammatory joint diseases caused by multiple factors which can affect many joints, such as hands, feet, hips, and knees. The typical symptoms of arthritis are chronic pain and deformity, affecting 340 million and 13 million people worldwide, respectively. By 2030, about 35% of the world's population will suffer from osteoarthritis. Rheumatoid arthritis has a high disability rate, which seriously threatens people's health and subsequently affects their quality of life. The high prevalence of arthritis causes severe economic burdens on individuals and society. An effective treatment plan is particularly important for patients with arthritis to improve their life quality.
The current treatment of arthritis includes medications, physical therapy, and surgical intervention, which are aimed at alleviating symptoms and reducing joint damage and disability. At present, most sports and surgical treatments mainly control pain symptoms and do not inhibit pathological changes. Clinically, traditional Chinese medicine such as Chinese herbal medicine and acupuncture, play an important role in arthritis treatment through delaying the pathology progression or alleviating pain. Traditional Chinese medicine mainly regulates the development of arthritis based on metabolic networks, transcriptional regulatory networks, and protein interaction networks. Furthermore, epigenetic alteration is also a common mechanism for the treatment of arthritis with traditional Chinese medicine. This special issue will focus on the treatment of osteoarthritis and rheumatoid arthritis with traditional Chinese medicine, reveal its molecular mechanism and provide a theoretical basis for further improving the drug efficacy in arthritis treatment.
This research topic mainly gathers the original researches and reviews that report arthritis treatment (osteoarthritis or rheumatic arthritis) with traditional Chinese medicine such as Chinese herbal medicine or acupuncture, or how the different factors such as kidney deficiency, blood stasis, and cold dampness influence the pathogenesis of arthritis.
Topics may include but are not limited to the following:
-The effect and mechanism of traditional Chinese herbal medicine on the treatment of arthritis through proteomics analysis, transcriptomics analysis, metabolomics analysis, and epigenetics analysis.
-Revealing the molecular mechanism of different factors (kidney deficiency, blood stasis, cold dampness) that cause arthritis through proteomics analysis, transcriptomics analysis, metabolomics analysis, and epigenetics analysis.
-The effect and mechanism of acupuncture on the treatment of arthritis through proteomics analysis, transcriptomics analysis, metabolomics analysis, and epigenetics analysis.
This special publication should be scientific, innovative, and published online after fully open, fair, and strict peer review. Once the article is online, it can be quoted.
