Mood disorders including bipolar disorder and major depressive disorder are common in the general population and produce a significant global disease burden. Although there are optimized guidelines for disease treatment and management, problems such as high disease recurrence and slow drug response still exist. To solve these problems, the pathogenesis of mood disorders needs to be explored deeply. It has been shown that in addition to mood symptoms, patients with mood disorders also have other detrimental manifestations, such as cognitive deficit, as well as metabolic and endocrine disturbances. It seems that mental illness may be a systemic disease, involving alterations in the brain and peripheral metabolic and endocrine function. However, cognitive impairment, as well as metabolic and endocrine changes in mood disorders is still not well understood. Clarifying the mechanisms underlying these clinical phenomenons lay the foundation for further therapeutic research, and then could make improvements in psychiatry.
Cognitive deficit is widely found in mood disorders and seriously affects the quality of life. This has received much attention from researchers, who make efforts to improve the cognitive function of the patients. In recent decades, the disturbance of metabolism and endocrine was also recognized in mood disorders, and it was considered to be associated with cognitive impairment. To date, studies referring to cognition, metabolism, and endocrine are not comprehensive enough. Therefore, this Research Topic aims to explore the relationships among cognition, metabolism and endocrine, and mood disorders. Both animal and human studies in the fields of neuroimaging, brain stimulation, electrophysiology, and metabolomics are welcome to submit.
Original studies and reviews on the aims of this Research Topic are acceptable. The following are some themes for reference.
1. Clinical or experimental studies on the relationship between cognition and mood disorders, as well as between metabolism and endocrine and mood disorders.
2. Clinical or experimental studies on the relationship between cognitive deficit and metabolic and endocrine disturbance in mood disorders.
3. Epidemiological studies on the association between metabolic and endocrine disturbance and the risk of mood disorders, and between mood disorders and the risk of metabolic and endocrine disturbance.
4. New methods in the assessment and methodology, such as neurobiological markers and neuroimaging indicators.
5. Differences in the relationships between disease, e.g. between major depressive disorder and bipolar disorder.
Mood disorders including bipolar disorder and major depressive disorder are common in the general population and produce a significant global disease burden. Although there are optimized guidelines for disease treatment and management, problems such as high disease recurrence and slow drug response still exist. To solve these problems, the pathogenesis of mood disorders needs to be explored deeply. It has been shown that in addition to mood symptoms, patients with mood disorders also have other detrimental manifestations, such as cognitive deficit, as well as metabolic and endocrine disturbances. It seems that mental illness may be a systemic disease, involving alterations in the brain and peripheral metabolic and endocrine function. However, cognitive impairment, as well as metabolic and endocrine changes in mood disorders is still not well understood. Clarifying the mechanisms underlying these clinical phenomenons lay the foundation for further therapeutic research, and then could make improvements in psychiatry.
Cognitive deficit is widely found in mood disorders and seriously affects the quality of life. This has received much attention from researchers, who make efforts to improve the cognitive function of the patients. In recent decades, the disturbance of metabolism and endocrine was also recognized in mood disorders, and it was considered to be associated with cognitive impairment. To date, studies referring to cognition, metabolism, and endocrine are not comprehensive enough. Therefore, this Research Topic aims to explore the relationships among cognition, metabolism and endocrine, and mood disorders. Both animal and human studies in the fields of neuroimaging, brain stimulation, electrophysiology, and metabolomics are welcome to submit.
Original studies and reviews on the aims of this Research Topic are acceptable. The following are some themes for reference.
1. Clinical or experimental studies on the relationship between cognition and mood disorders, as well as between metabolism and endocrine and mood disorders.
2. Clinical or experimental studies on the relationship between cognitive deficit and metabolic and endocrine disturbance in mood disorders.
3. Epidemiological studies on the association between metabolic and endocrine disturbance and the risk of mood disorders, and between mood disorders and the risk of metabolic and endocrine disturbance.
4. New methods in the assessment and methodology, such as neurobiological markers and neuroimaging indicators.
5. Differences in the relationships between disease, e.g. between major depressive disorder and bipolar disorder.