Vaccines and immunotherapy against fungi: the new frontier

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Editorial

25 January 2013

Vaccines and immunotherapy against fungi: the new frontier

Joshua D. Nosanchuk

and

Carlos P. Taborda

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1 citations

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Joshua D Nosanchuk

Albert Einstein College of Medicine

Carlos Pelleschi Taborda

University of São Paulo

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Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. Moreover, our present potent antifungal armamentarium fails to eradicate fungal pathogens from certain compromised hosts. Additionally, invasive fungal diseases continue to have unacceptably high mortality rates. A growing body of work has focused on the utility of vaccines and/or immunotherapy as a powerful tool in combating mycoses, either for the active treatment, as an adjuvant, or in the prevention of specific fungal pathogens. This Research Topic will detail the exciting progress in developing vaccines and immunotherapy for fungi.

Invasive fungal diseases have increased many fold over the past 50 years. Current treatment regimens typically require prolonged administration of antifungal medications that can have significant toxicity. Moreover, our present potent antifungal armamentarium fails to eradicate fungal pathogens from certain compromised hosts. Additionally, invasive fungal diseases continue to have unacceptably high mortality rates. A growing body of work has focused on the utility of vaccines and/or immunotherapy as a powerful tool in combating mycoses, either for the active treatment, as an adjuvant, or in the prevention of specific fungal pathogens. This Research Topic will detail the exciting progress in developing vaccines and immunotherapy for fungi.

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Editors

Joshua D Nosanchuk

Albert Einstein College of Medicine

Carlos Pelleschi Taborda

University of São Paulo

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90,011 Total views

68,538 Article views

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1,896 Topic views

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Frontiers in Microbiology

Fungi and Their Interactions

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