Endocrine oncology includes tumors of hormone-producing glands such as the pancreas, thyroid, parathyroid, pituitary and adrenal gland. Dog and cats suffering from endocrine cancers benefit from a multidisciplinary approach by specialists in the fields of endocrinology, surgery, radiation therapy and nuclear medicine. The benefit of multidisciplinary teams is that they are able to provide a wide range of care from standard of care diagnostics, imaging studies and treatments to cutting-edge molecular diagnostics and state-of the-art surgical procedures. Advances in veterinary genomics also open up the possibility of targeted drug therapies for canine and feline endocrine cancers in the near future.
Recent genomic studies have improved our understanding of underlying molecular mechanisms of certain endocrine cancers. E.g. transcriptomic analysis by RNA sequencing characterized malignant progression of canine insulinoma from normal tissue to metastatic disease and whole genome sequencing provided novel insight into the genetic causes of canine familial thyroid follicular cell carcinoma, which enabled the development of a genetic test to screen susceptible dogs. Despite recent advances, the underlying mechanisms of tumorigenesis of endocrine cancers in dogs and cats are still largely unknown. A better understanding of the molecular background of these tumors could help to identify novel drug targets improving clinical outcome.
This Research Topic aims to publish original research work, reviews or case reports that provide readers with an update on the most recent advances in veterinary endocrine oncology. Examples of manuscript topics that will be considered are:
- New insights into molecular pathogenesis;
- Advances in diagnostic tests and imaging;
- Novel (prognostic) biomarkers;
- Novel medical and/or surgical treatment strategies;
- Comparative aspects of endocrine cancers in the context of “One Health”.
This Research Topic will provide the latest information on the above topics and will be of interest to those scientists and clinicians working in the area of veterinary endocrine oncology.
Endocrine oncology includes tumors of hormone-producing glands such as the pancreas, thyroid, parathyroid, pituitary and adrenal gland. Dog and cats suffering from endocrine cancers benefit from a multidisciplinary approach by specialists in the fields of endocrinology, surgery, radiation therapy and nuclear medicine. The benefit of multidisciplinary teams is that they are able to provide a wide range of care from standard of care diagnostics, imaging studies and treatments to cutting-edge molecular diagnostics and state-of the-art surgical procedures. Advances in veterinary genomics also open up the possibility of targeted drug therapies for canine and feline endocrine cancers in the near future.
Recent genomic studies have improved our understanding of underlying molecular mechanisms of certain endocrine cancers. E.g. transcriptomic analysis by RNA sequencing characterized malignant progression of canine insulinoma from normal tissue to metastatic disease and whole genome sequencing provided novel insight into the genetic causes of canine familial thyroid follicular cell carcinoma, which enabled the development of a genetic test to screen susceptible dogs. Despite recent advances, the underlying mechanisms of tumorigenesis of endocrine cancers in dogs and cats are still largely unknown. A better understanding of the molecular background of these tumors could help to identify novel drug targets improving clinical outcome.
This Research Topic aims to publish original research work, reviews or case reports that provide readers with an update on the most recent advances in veterinary endocrine oncology. Examples of manuscript topics that will be considered are:
- New insights into molecular pathogenesis;
- Advances in diagnostic tests and imaging;
- Novel (prognostic) biomarkers;
- Novel medical and/or surgical treatment strategies;
- Comparative aspects of endocrine cancers in the context of “One Health”.
This Research Topic will provide the latest information on the above topics and will be of interest to those scientists and clinicians working in the area of veterinary endocrine oncology.