Autoinflammatory Diseases: From Genes To Bedside

168.1K

views

59

authors

14

articles

Autoinflammatory Diseases: From Genes To Bedside

168.1K

views

59

authors

14

articles

Editorial

19 June 2020

Editorial: Autoinflammatory Diseases: From Genes to Bedside

Ivona Aksentijevich

,

Alessandra Soriano

and

José Hernández-Rodríguez

4,613 views

9 citations

Editors

2

Alessandra Soriano

Santa Maria Nuova Hospital

José Hernández-Rodríguez

Clinical Unit of Autoinflammatory Diseases and Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clinic, IDIBAPS, University of Barcelona

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Over the past decades, the discovery of the genes involved in autoinflammatory syndromes together with the insights into their innate immune mechanisms have revolutionized the paradigm of definition, classification and therapeutical approach of the different autoinflammatory diseases. The research of pathogenic mechanisms in autoinflammation has been focused in the knowledge of inflammasomes, the identification of molecular links between disease-causing mutations, altered pathways of inflammation and final disease phenotypes, and the identification of molecular targets, which has finally changed the quality of life and the survival of patients with these previous untreatable diseases.
All these facts make autoinflammatory diseases one of the most active fields of translational research nowadays.

As two researchers deeply interested in autoinflammatory syndromes, we propose to gather the world top experts in autoinflammation and autoinflammatory diseases for a new and attractive Research Topic in Frontiers in Immunology, which will include scientific articles covering the spectrum of all the mentioned aspects of this fascinating field.

Over the past decades, the discovery of the genes involved in autoinflammatory syndromes together with the insights into their innate immune mechanisms have revolutionized the paradigm of definition, classification and therapeutical approach of the different autoinflammatory diseases. The research of pathogenic mechanisms in autoinflammation has been focused in the knowledge of inflammasomes, the identification of molecular links between disease-causing mutations, altered pathways of inflammation and final disease phenotypes, and the identification of molecular targets, which has finally changed the quality of life and the survival of patients with these previous untreatable diseases.
All these facts make autoinflammatory diseases one of the most active fields of translational research nowadays.

As two researchers deeply interested in autoinflammatory syndromes, we propose to gather the world top experts in autoinflammation and autoinflammatory diseases for a new and attractive Research Topic in Frontiers in Immunology, which will include scientific articles covering the spectrum of all the mentioned aspects of this fascinating field.

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Editors

Alessandra Soriano

Santa Maria Nuova Hospital

José Hernández-Rodríguez

Clinical Unit of Autoinflammatory Diseases and Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clinic, IDIBAPS, University of Barcelona

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168,076 Total views

128,107 Article views

36,760 Article downloads

3,209 Topic views

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Frontiers in Immunology

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