Arthropod-borne viruses (arboviruses) have emerged rapidly and continuously. Due to high urbanization, increased travel, and climate change, arboviruses have spread globally and are responsible for an increasing number of disease outbreaks, becoming a serious challenge to world public health. For example, dengue viruses are responsible for more than 400 million annual infections worldwide by one of its four serotypes (DENV1-4). In addition, the emergence of chikungunya and Zika viruses in dengue-endemic regions has created alarming scenarios. In urban settings, all these three viruses are epidemiologically synergic due to sharing common hosts (humans) and mosquito vectors (mainly A. aegypti). Therefore, these viruses are governed by similar biological, ecological, and economic factors. In addition to overlapping geographically, they also have similar seasonality and attack rates. Simultaneous outbreaks of arboviruses have now been observed in many regions worldwide. In addition to Dengue, Zika, and Chikungunya viruses, other arboviruses which have not been studied as well, such as Yellow fever, West Nile, Mayaro, and Japanese encephalitis viruses, have also been reported to co-circulate in urban and peri-urban areas worldwide.
Arboviruses continue to emerge, and the occurrence of coinfection may increase as well. Unfortunately, we know fundamentally little about the process and consequences of coinfections. For example, it is unclear whether the coinfection of arboviruses can alter human disease outcomes. In addition, we do not know if people are infected by multiple mosquitoes or by the same mosquito transmitting numerous viruses. Moreover, it is unclear if simultaneous virus outbreaks involving the same vectors and hosts alter transmission dynamics. Therefore, in this Research Topic, we are interested in Original Research and Reviews that can contribute to an updated and improved knowledge regarding arboviral coinfection, co-transmission, and co-circulation.
Little is known about the process and consequences of coinfections. For example, it is unclear whether coinfection of arboviruses can alter human disease. In addition, we do not know if people are infected by multiple mosquitoes or by the same mosquito transmitting numerous viruses. Moreover, it is unclear if simultaneous virus outbreaks involving the same vectors and hosts alter transmission dynamics. Therefore, in this Research Topic, we are interested in original articles and systematic reviews that can contribute to an updated and improved knowledge regarding arboviral coinfection, co-transmission, and co-circulation.
In this Research Topic, we are interested in an updated and improved understanding of arboviral coinfection, co-transmission, and co-circulation. Submissions on the following themes are encouraged:
• New evidence and mechanisms of coinfection of arboviruses
• Further evidence of co-circulation of different arboviruses
• New evidence and mechanisms of co-transmission of different arboviruses
• Mechanisms of pathogenesis in coinfection of arboviruses.
Arthropod-borne viruses (arboviruses) have emerged rapidly and continuously. Due to high urbanization, increased travel, and climate change, arboviruses have spread globally and are responsible for an increasing number of disease outbreaks, becoming a serious challenge to world public health. For example, dengue viruses are responsible for more than 400 million annual infections worldwide by one of its four serotypes (DENV1-4). In addition, the emergence of chikungunya and Zika viruses in dengue-endemic regions has created alarming scenarios. In urban settings, all these three viruses are epidemiologically synergic due to sharing common hosts (humans) and mosquito vectors (mainly A. aegypti). Therefore, these viruses are governed by similar biological, ecological, and economic factors. In addition to overlapping geographically, they also have similar seasonality and attack rates. Simultaneous outbreaks of arboviruses have now been observed in many regions worldwide. In addition to Dengue, Zika, and Chikungunya viruses, other arboviruses which have not been studied as well, such as Yellow fever, West Nile, Mayaro, and Japanese encephalitis viruses, have also been reported to co-circulate in urban and peri-urban areas worldwide.
Arboviruses continue to emerge, and the occurrence of coinfection may increase as well. Unfortunately, we know fundamentally little about the process and consequences of coinfections. For example, it is unclear whether the coinfection of arboviruses can alter human disease outcomes. In addition, we do not know if people are infected by multiple mosquitoes or by the same mosquito transmitting numerous viruses. Moreover, it is unclear if simultaneous virus outbreaks involving the same vectors and hosts alter transmission dynamics. Therefore, in this Research Topic, we are interested in Original Research and Reviews that can contribute to an updated and improved knowledge regarding arboviral coinfection, co-transmission, and co-circulation.
Little is known about the process and consequences of coinfections. For example, it is unclear whether coinfection of arboviruses can alter human disease. In addition, we do not know if people are infected by multiple mosquitoes or by the same mosquito transmitting numerous viruses. Moreover, it is unclear if simultaneous virus outbreaks involving the same vectors and hosts alter transmission dynamics. Therefore, in this Research Topic, we are interested in original articles and systematic reviews that can contribute to an updated and improved knowledge regarding arboviral coinfection, co-transmission, and co-circulation.
In this Research Topic, we are interested in an updated and improved understanding of arboviral coinfection, co-transmission, and co-circulation. Submissions on the following themes are encouraged:
• New evidence and mechanisms of coinfection of arboviruses
• Further evidence of co-circulation of different arboviruses
• New evidence and mechanisms of co-transmission of different arboviruses
• Mechanisms of pathogenesis in coinfection of arboviruses.