About this Research Topic
Resolution and Regeneration of Inflammation in Lung and Brain Disorders
Uncontrolled inflammation could cause a number of pulmonary and brain diseases, such as acute respiratory distress syndrome (ARDS), allergic airway inflammation, aging, and cognitive impairment. The process of inflammation resolution is responsible for turning inflammation off, which traditionally was viewed as a passive process. However, numerous studies in recent years have shown that resolution is an active process characterized by a series of actions orchestrated by a complex group of mediators that control cellular events necessary to remove inflammatory cells from sites of infection or injury and restore tissue homeostasis. Therefore, it's an important topic to discuss the interaction between resolution and regeneration during inflammation-induced diseases, such as acute lung injury, asthma, aging, and cognitive impairment.
A host's ability to prevent tissue damage and re-establish homeostasis depends on the prompt resolution of inflammation because prolonged inflammatory responses can cause significant tissue destruction. However, recent studies mainly focus on the initiation of inflammatory responses. Therefore, deeper comprehension of resolution and regeneration during inflammatory diseases may lead to intriguing alternate strategies for improving existing treatments.
This Research Topic is centered on recent significant advancements in the interconnections between resolution and regeneration in lung and brain disorders, gathering excellent insights, discoveries, and techniques in understanding the precise interplay mechanism in various inflammatory diseases. We especially encourage the following subjects, although they are not restricted to them:
• Which innate and adaptive immune cells are involved in the resolution/regeneration during acute lung injury, asthma, aging, and cognitive impairment?
• The specific roles of innate and adaptive immune cells in providing dampening proinflammatory signals and specialized pro-resolving mediators during the resolution/regeneration process.
• The applications and roles of multi-omics data like metagenome, metabolism, immune Repertoire, and Single-cell sequencing, with a focus on immune responses and immune-mediated inflammation.
• Innovations in new technology and ideas for evaluating and observing the resolution/regeneration process directly or indirectly acting on inflammation and immunity.
Uncontrolled inflammation could cause a number of pulmonary and brain diseases, such as acute respiratory distress syndrome (ARDS), allergic airway inflammation, aging, and cognitive impairment. The process of inflammation resolution is responsible for turning inflammation off, which traditionally was viewed as a passive process. However, numerous studies in recent years have shown that resolution is an active process characterized by a series of actions orchestrated by a complex group of mediators that control cellular events necessary to remove inflammatory cells from sites of infection or injury and restore tissue homeostasis. Therefore, it's an important topic to discuss the interaction between resolution and regeneration during inflammation-induced diseases, such as acute lung injury, asthma, aging, and cognitive impairment.
A host's ability to prevent tissue damage and re-establish homeostasis depends on the prompt resolution of inflammation because prolonged inflammatory responses can cause significant tissue destruction. However, recent studies mainly focus on the initiation of inflammatory responses. Therefore, deeper comprehension of resolution and regeneration during inflammatory diseases may lead to intriguing alternate strategies for improving existing treatments.
This Research Topic is centered on recent significant advancements in the interconnections between resolution and regeneration in lung and brain disorders, gathering excellent insights, discoveries, and techniques in understanding the precise interplay mechanism in various inflammatory diseases. We especially encourage the following subjects, although they are not restricted to them:
• Which innate and adaptive immune cells are involved in the resolution/regeneration during acute lung injury, asthma, aging, and cognitive impairment?
• The specific roles of innate and adaptive immune cells in providing dampening proinflammatory signals and specialized pro-resolving mediators during the resolution/regeneration process.
• The applications and roles of multi-omics data like metagenome, metabolism, immune Repertoire, and Single-cell sequencing, with a focus on immune responses and immune-mediated inflammation.
• Innovations in new technology and ideas for evaluating and observing the resolution/regeneration process directly or indirectly acting on inflammation and immunity.
Keywords: Inflammation, injury, resolution, regeneration, Lung, Brain
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