Mood disorders refer to a group of disorders characterized by significant and persistent changes in mood or emotion caused by various reasons, mainly including depressive disorder (MDD) and bipolar disorder (BPD). The clinical characteristics of mood disorders are mainly emotional upsurge or depression, often accompanied by corresponding cognitive and behavioral changes. Besides, there can be hallucinations, delusions, and other psychotic symptoms. Most patients have the tendency of recurrent episodes, and some patients may have residual symptoms or become chronic. Mood disorders are associated with a higher risk of suicide and a higher burden of disease. However, the etiology and pathogenesis of mood disorders are still unclear, and the lack of neurobiological markers leads to difficulties in clinical diagnosis and treatment.
This research topic welcomes original research and review articles that can analyze the etiology or pathogenesis of mood disorders, optimize pharmacological treatment strategies, or screen biomarkers with data from brain imaging and stimulation. This topic aims to answer two main questions.
1. What is the specific biomarker or combination of biomarkers for mood disorders from the perspective of brain imaging and nerve stimulation?
2. How can these biomarkers or combinations of biomarkers be translated to clinical diagnosis and treatment?
Sub-themes may include but are not limited to the following:
(1) Exploring the etiology, pathogenesis, diagnosis, and treatment of mood disorders and their underlying neurobiological mechanisms.
(2) Differential diagnosis of early-onset mood disorders
(3) Exploration of the combination of techniques under multiple modalities, such as neurophysiological and neuroimaging studies with genetic analysis
(4) Optimization of pharmacological treatment strategies for mood disorders and exploration of the neurobiological mechanisms of pharmacological interventions and mood disorders
Mood disorders refer to a group of disorders characterized by significant and persistent changes in mood or emotion caused by various reasons, mainly including depressive disorder (MDD) and bipolar disorder (BPD). The clinical characteristics of mood disorders are mainly emotional upsurge or depression, often accompanied by corresponding cognitive and behavioral changes. Besides, there can be hallucinations, delusions, and other psychotic symptoms. Most patients have the tendency of recurrent episodes, and some patients may have residual symptoms or become chronic. Mood disorders are associated with a higher risk of suicide and a higher burden of disease. However, the etiology and pathogenesis of mood disorders are still unclear, and the lack of neurobiological markers leads to difficulties in clinical diagnosis and treatment.
This research topic welcomes original research and review articles that can analyze the etiology or pathogenesis of mood disorders, optimize pharmacological treatment strategies, or screen biomarkers with data from brain imaging and stimulation. This topic aims to answer two main questions.
1. What is the specific biomarker or combination of biomarkers for mood disorders from the perspective of brain imaging and nerve stimulation?
2. How can these biomarkers or combinations of biomarkers be translated to clinical diagnosis and treatment?
Sub-themes may include but are not limited to the following:
(1) Exploring the etiology, pathogenesis, diagnosis, and treatment of mood disorders and their underlying neurobiological mechanisms.
(2) Differential diagnosis of early-onset mood disorders
(3) Exploration of the combination of techniques under multiple modalities, such as neurophysiological and neuroimaging studies with genetic analysis
(4) Optimization of pharmacological treatment strategies for mood disorders and exploration of the neurobiological mechanisms of pharmacological interventions and mood disorders
