Veterinary pathogens, especially emerging and re-emerging pathogens, are serious threats to dairy, meat, and poultry industries and are responsible for huge socio-economic losses worldwide. The present lack of effective diagnostics, therapeutics, and control measures leaves farmers at perpetual great risk of financially disastrous outbreaks of several infectious diseases in livestock. Thus far, limited information is available on the large-scale genomics, genetic diversity, genotyping, phylogenetic analyses, emerging antimicrobials resistance, proteomics, and vaccines of most of the strains of pathogens. Without effective preventive strategies and diagnostic tools, asymptomatic carrier animals rapidly infect entire herds/flocks and therapeutic intervention comes too late. Additionally, therapeutics and vaccines specific to isolates have rarely been identified or developed, and the high cost and poor accessibility of existing biologics greatly restricts their use by farmers around the world. These conditions contribute to the costly and miserable perpetuation of infections in livestock. Therefore, employment of advanced molecular approaches is direly needed for the improved diagnostic, preventive, therapeutic and control strategies against infectious diseases.
Animals’ infectious agents, particularly viruses and bacteria, are rapidly evolving and resultantly more robust strains/isolates of these pathogens are emerging and re-emerging round the world. Therefore, in this issue we will focus on the exploration of full genomes using NGS and proteomes of infectious agents for the genotyping, geno-plasticity, molecular epidemiology, phylogenetic analyses, AMR, and functional genomics, ultimately for the improved therapeutics and vaccines against serious livestock diseases.
Veterinary Pathogens (viruses and bacteria) include:
- Whole Genome Sequencing
- Proteome analyses
- Comparative genome/proteome analyses
- Genotyping
- Molecular Epidemiology
- Genetic Diversity/Evolution
- Phylogenetic analyses
- Antimicrobials resistance
- Pathogenesis
- Host-Pathogen Interaction
- Reverse Vaccinology
- Potential candidate genes/Therapeutics/Vaccines.
Veterinary pathogens, especially emerging and re-emerging pathogens, are serious threats to dairy, meat, and poultry industries and are responsible for huge socio-economic losses worldwide. The present lack of effective diagnostics, therapeutics, and control measures leaves farmers at perpetual great risk of financially disastrous outbreaks of several infectious diseases in livestock. Thus far, limited information is available on the large-scale genomics, genetic diversity, genotyping, phylogenetic analyses, emerging antimicrobials resistance, proteomics, and vaccines of most of the strains of pathogens. Without effective preventive strategies and diagnostic tools, asymptomatic carrier animals rapidly infect entire herds/flocks and therapeutic intervention comes too late. Additionally, therapeutics and vaccines specific to isolates have rarely been identified or developed, and the high cost and poor accessibility of existing biologics greatly restricts their use by farmers around the world. These conditions contribute to the costly and miserable perpetuation of infections in livestock. Therefore, employment of advanced molecular approaches is direly needed for the improved diagnostic, preventive, therapeutic and control strategies against infectious diseases.
Animals’ infectious agents, particularly viruses and bacteria, are rapidly evolving and resultantly more robust strains/isolates of these pathogens are emerging and re-emerging round the world. Therefore, in this issue we will focus on the exploration of full genomes using NGS and proteomes of infectious agents for the genotyping, geno-plasticity, molecular epidemiology, phylogenetic analyses, AMR, and functional genomics, ultimately for the improved therapeutics and vaccines against serious livestock diseases.
Veterinary Pathogens (viruses and bacteria) include:
- Whole Genome Sequencing
- Proteome analyses
- Comparative genome/proteome analyses
- Genotyping
- Molecular Epidemiology
- Genetic Diversity/Evolution
- Phylogenetic analyses
- Antimicrobials resistance
- Pathogenesis
- Host-Pathogen Interaction
- Reverse Vaccinology
- Potential candidate genes/Therapeutics/Vaccines.