This Research Topic is in partnership with the
The 5th Brainstorming Research Assembly for Young Neuroscientists (Brayn) conference.
Neuroscience research is evolving at a remarkable pace due to the continuous development of tools and methodologies for studying the central and peripheral nervous system. Advances in this field have been made possible through complementary approaches based on preclinical models, which have led to a better understanding of brain functioning, as well as the cellular and molecular mechanisms involved in nervous system disorders. In particular, significant progresses have been made in the last years regarding novel human in vitro models, such as brain organoids, derived from human induced pluripotent stem cells. However, research protocols robustly validated and reproducible across laboratories require a considerable investment in time and resources. Thus, open access sharing of established protocols is of utmost importance to promote solid and rapid progresses in the field.
With this Research Topic we aim at discussing and sharing the major methods currently available to investigate different aspects of neuroscience research, focusing on both neuronal and non-neuronal cells. Original in vitro, ex vivo and in vivo procedures, established to investigate different biological questions about brain function and dysfunction, will be collected here. In particular, we will welcome detailed protocols for functional assays and methods to assess the heterogeneity of brain cell populations in different brain regions, across age and sex; protocols to generate or manipulate in vitro and ex vivo models; protocols for in vivo assays, ranging from electrophysiological recordings, to imaging and behavioral testing.
For this purpose, we particularly welcome the submission of Methods and Review articles focusing on, but not limited to:
• Detailed protocols aimed at dissecting and studying the diverse function of neuronal and non-neuronal cells in neurodevelopment, in physiological states, as well as in neurodegeneration
• Literature reviews on state-of-the-art methodologies, presenting pros and cons alongside future developments.
• Perspective articles presenting possible expansion/applications in neuroscience of methods/tools originally applied in other fields
This Research Topic is in partnership with the
The 5th Brainstorming Research Assembly for Young Neuroscientists (Brayn) conference.
Neuroscience research is evolving at a remarkable pace due to the continuous development of tools and methodologies for studying the central and peripheral nervous system. Advances in this field have been made possible through complementary approaches based on preclinical models, which have led to a better understanding of brain functioning, as well as the cellular and molecular mechanisms involved in nervous system disorders. In particular, significant progresses have been made in the last years regarding novel human in vitro models, such as brain organoids, derived from human induced pluripotent stem cells. However, research protocols robustly validated and reproducible across laboratories require a considerable investment in time and resources. Thus, open access sharing of established protocols is of utmost importance to promote solid and rapid progresses in the field.
With this Research Topic we aim at discussing and sharing the major methods currently available to investigate different aspects of neuroscience research, focusing on both neuronal and non-neuronal cells. Original in vitro, ex vivo and in vivo procedures, established to investigate different biological questions about brain function and dysfunction, will be collected here. In particular, we will welcome detailed protocols for functional assays and methods to assess the heterogeneity of brain cell populations in different brain regions, across age and sex; protocols to generate or manipulate in vitro and ex vivo models; protocols for in vivo assays, ranging from electrophysiological recordings, to imaging and behavioral testing.
For this purpose, we particularly welcome the submission of Methods and Review articles focusing on, but not limited to:
• Detailed protocols aimed at dissecting and studying the diverse function of neuronal and non-neuronal cells in neurodevelopment, in physiological states, as well as in neurodegeneration
• Literature reviews on state-of-the-art methodologies, presenting pros and cons alongside future developments.
• Perspective articles presenting possible expansion/applications in neuroscience of methods/tools originally applied in other fields