The role of coronary functional test has been emphasized in the field of coronary artery disease, as it provides valuable information regarding coronary blood flow reserve and microvascular resistance. In obstructive coronary artery disease, functional flow reserve (FFR) is an important physiologic parameter that allows functional measurement of epicardial artery, therefore differentiates stenotic lesions at the grey zone. Additionally, angiography-derived quantitative flow reserve (QFR) is a novel method to measure coronary functional flow, has been testified to be equivocal to FFR. In non-obstructive coronary artery disease, which takes up a significant proportion of all candidates indicative of coronary angiography, coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) are served to measure the microvascular resistance, in order to diagnose coronary microvascular dysfunction. Apart from diagnosis, parameters generated from coronary function test can be used in prognostic assessment for coronary artery disease, such as re-hospitalization, quality of life and major adverse cardiovascular events. Nevertheless, the use of coronary functional test is uncommon, due to lack of public awareness, invasiveness, sophisticating procedures and shortage of technique support.
In this research topic, we would like to create a forum for the clinical use of novel techniques that generates physiologic parameters that equivalent to FFR, CFR and IMR, but in a non-invasive, time-saving, and cost-saving manner, as well as the exploration of clinical significance of coronary functional test in the prognostic assessment of coronary artery disease, especially those with coronary microvascular dysfunction.
We welcome submissions in the following subtopic, but not limited to:
1. The performance of quantitative flow ration (QFR) in comparison to FFR, on measuring coronary flow reserve.
2. Non-invasive modality (echocardiography, CT, MR, PET, artificial intelligence, etc.) that could be used to assess coronary flow reserve and/or microvascular resistance.
3. The performance of coronary functional test on predicting adverse clinical outcome in patients with coronary artery disease.
4. The performance of coronary functional test on guiding medical treatment (nicorandil, trimetazidine, etc) in coronary artery disease.
5. The performance of coronary functional test on assessing effectiveness of medical treatment (nicorandil, trimetazidine, etc), especially on the recovery of microvascular dysfunction.
The role of coronary functional test has been emphasized in the field of coronary artery disease, as it provides valuable information regarding coronary blood flow reserve and microvascular resistance. In obstructive coronary artery disease, functional flow reserve (FFR) is an important physiologic parameter that allows functional measurement of epicardial artery, therefore differentiates stenotic lesions at the grey zone. Additionally, angiography-derived quantitative flow reserve (QFR) is a novel method to measure coronary functional flow, has been testified to be equivocal to FFR. In non-obstructive coronary artery disease, which takes up a significant proportion of all candidates indicative of coronary angiography, coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) are served to measure the microvascular resistance, in order to diagnose coronary microvascular dysfunction. Apart from diagnosis, parameters generated from coronary function test can be used in prognostic assessment for coronary artery disease, such as re-hospitalization, quality of life and major adverse cardiovascular events. Nevertheless, the use of coronary functional test is uncommon, due to lack of public awareness, invasiveness, sophisticating procedures and shortage of technique support.
In this research topic, we would like to create a forum for the clinical use of novel techniques that generates physiologic parameters that equivalent to FFR, CFR and IMR, but in a non-invasive, time-saving, and cost-saving manner, as well as the exploration of clinical significance of coronary functional test in the prognostic assessment of coronary artery disease, especially those with coronary microvascular dysfunction.
We welcome submissions in the following subtopic, but not limited to:
1. The performance of quantitative flow ration (QFR) in comparison to FFR, on measuring coronary flow reserve.
2. Non-invasive modality (echocardiography, CT, MR, PET, artificial intelligence, etc.) that could be used to assess coronary flow reserve and/or microvascular resistance.
3. The performance of coronary functional test on predicting adverse clinical outcome in patients with coronary artery disease.
4. The performance of coronary functional test on guiding medical treatment (nicorandil, trimetazidine, etc) in coronary artery disease.
5. The performance of coronary functional test on assessing effectiveness of medical treatment (nicorandil, trimetazidine, etc), especially on the recovery of microvascular dysfunction.