Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

222.9K

views

114

authors

20

articles

Editorial

22 March 2018

Editorial: Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

Kulmira Nurgali

,

R. Thomas Jagoe

and

Raquel Abalo

86,750 views

794 citations

Editors

3

Rey Juan Carlos University

Kulmira Nurgali

Institute of Health and Sport, College of Health and Biomedicine, Victoria University

McGill University

Impact

Fetching...

About

The present Research Topic is based on the following facts:

- Cancer is one of the diseases with higher prevalence and morbi-mortality nowadays.
- Cancer chemotherapy is still greatly feared by the patients (and clinicians) because of the known adverse effects that may occur: nausea, emesis, alterations in blood-cell counting (anaemia, altered immune system and altered clotting), peripheral neuropathy, heart malfunctioning, kidney damage, cognitive loss…
- Current antineoplastic treatments have increased survival and we do not know much yet about the sequelae that they may leave in the survivors: cognitive dysfuntions, cardiovascular alterations, higher risk to gastrointestinal diseases, permanent sensory dysfuntions…
- Current prophylactic treatments to avoid/reduce/treat chemotherapy-induced adverse effects occurring during cycles are not always 100 per cent efficacious (or they may lose efficacy throughout cycles), may not be useful to avoid sequelae, or maybe even add their own side effects to patient discomfort…
- New approaches capable of improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed.

We call authors from all over the world to submit original basic or clinical research or review articles describing the adverse effects of cancer chemotherapy and/or possible new strategies to avoid/reduce these effects, particularly those occurring in the long-term (sequelae), which are still highly unknown.

The present Research Topic is based on the following facts:

- Cancer is one of the diseases with higher prevalence and morbi-mortality nowadays.
- Cancer chemotherapy is still greatly feared by the patients (and clinicians) because of the known adverse effects that may occur: nausea, emesis, alterations in blood-cell counting (anaemia, altered immune system and altered clotting), peripheral neuropathy, heart malfunctioning, kidney damage, cognitive loss…
- Current antineoplastic treatments have increased survival and we do not know much yet about the sequelae that they may leave in the survivors: cognitive dysfuntions, cardiovascular alterations, higher risk to gastrointestinal diseases, permanent sensory dysfuntions…
- Current prophylactic treatments to avoid/reduce/treat chemotherapy-induced adverse effects occurring during cycles are not always 100 per cent efficacious (or they may lose efficacy throughout cycles), may not be useful to avoid sequelae, or maybe even add their own side effects to patient discomfort…
- New approaches capable of improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed.

We call authors from all over the world to submit original basic or clinical research or review articles describing the adverse effects of cancer chemotherapy and/or possible new strategies to avoid/reduce these effects, particularly those occurring in the long-term (sequelae), which are still highly unknown.

Download ebook

Share

Editors

Rey Juan Carlos University

Kulmira Nurgali

Institute of Health and Sport, College of Health and Biomedicine, Victoria University

McGill University

Impact

222,882 Total views

163,688 Article views

50,792 Article downloads

8,402 Topic views

Published In

Journal Thumbnail

Frontiers in Pharmacology

Pharmacology of Anti-Cancer Drugs

Journal Thumbnail

Frontiers in Oncology

Pharmacology of Anti-Cancer Drugs

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic