Pain is an unpleasant sensory and emotional experience and the most frequent causes for patients to seek medical care. Persistent chronic pain affects millions of people worldwide, causing low quality of health and emotional status, as well as posing a significant social and economic burden. Chronic pain is the long-standing pain that are classified as different types, including chronic primary pain and secondary pain types caused by various diseases. The complexity of cause and symptom in chronic pain is associated with changes in different levels of nervous system, from molecular interaction, synaptic connection, cellular response, and neural circuits. The development of new treatments to manage chronic pain shall base on the better standing of the neuropathological mechanism underlying the symptom, the exploration on the methods of a better diagnosis, and the communication of clinical application standards and results.
We launch this Research Topic, aiming to bring together a collection of papers focusing on the neuropathological mechanism of the formation and development of chronic pain, the new technology of chronic pain diagnosis and the result of novel treatment. These insights will bring together researches focusing on the chronic pain and the encourage the discussion on how to achieve better outcome. Original articles, reviews, and focus articles related to basic, translational, and clinical research are all welcome.
We look forward to the articles on the following topics, including, but not limited to:
• Neurodegenerative processes and related signaling pathways of secondary chronic pain caused by different diseases.
• The pathogenesis of chronic primary pain and its relationship with biological, psychological, and social factors.
• Application of the latest neuroimaging techniques in the differential diagnosis and action of chronic pain.
• New drugs or innovative use of traditional medicines, minimally invasive interventions, psychotherapies for chronic pain.
• Expert consensus or guidelines for diagnosis and treatment of chronic pain diseases.
Pain is an unpleasant sensory and emotional experience and the most frequent causes for patients to seek medical care. Persistent chronic pain affects millions of people worldwide, causing low quality of health and emotional status, as well as posing a significant social and economic burden. Chronic pain is the long-standing pain that are classified as different types, including chronic primary pain and secondary pain types caused by various diseases. The complexity of cause and symptom in chronic pain is associated with changes in different levels of nervous system, from molecular interaction, synaptic connection, cellular response, and neural circuits. The development of new treatments to manage chronic pain shall base on the better standing of the neuropathological mechanism underlying the symptom, the exploration on the methods of a better diagnosis, and the communication of clinical application standards and results.
We launch this Research Topic, aiming to bring together a collection of papers focusing on the neuropathological mechanism of the formation and development of chronic pain, the new technology of chronic pain diagnosis and the result of novel treatment. These insights will bring together researches focusing on the chronic pain and the encourage the discussion on how to achieve better outcome. Original articles, reviews, and focus articles related to basic, translational, and clinical research are all welcome.
We look forward to the articles on the following topics, including, but not limited to:
• Neurodegenerative processes and related signaling pathways of secondary chronic pain caused by different diseases.
• The pathogenesis of chronic primary pain and its relationship with biological, psychological, and social factors.
• Application of the latest neuroimaging techniques in the differential diagnosis and action of chronic pain.
• New drugs or innovative use of traditional medicines, minimally invasive interventions, psychotherapies for chronic pain.
• Expert consensus or guidelines for diagnosis and treatment of chronic pain diseases.