As we enter the third decade of the 21st Century, food allergy continues to be a growing public health concern. To combat this, scientists have successfully developed novel basic and translational animal models to make major advances in the fast-growing field of food allergy. These models are critical to allow scientists to better understand the immunological mechanisms that drive the development of allergic responses to food and develop novel therapeutic strategies for patients suffering from food allergies.
Although key advances have been made to understand how the immune system reacts to mount allergic responses to food, more work needs to be done to define how these immune reactions take place. Immune cells that initially respond to initiate and develop an immunological microenvironment conducive to allow sensitization to a particular food, as well as the antigen presenting cells that activate food allergen-specific T cells, need additional study to better understand the full picture of food-induced immune responses. Whether the immune system mounts a similar response to each type of food allergen (e.g. peanut, shellfish, milk, soy) remains an additional open question. While research in food allergy has made great progress, especially in recent years, much more remains to be learned.
This research topic intends to highlight basic and translational studies in the field of food allergy. The scope of this topic includes work that elucidates immunological mechanisms which contribute to the development of food allergy. We also want to highlight work that describes translational models that work to inhibit, treat, or drive tolerance in food allergy. We are interested in original research articles, reviews, and protocols that offer insight into how food allergy develops and how it could be treated. In vivo mechanistic studies that reveal novel immunological insight into possible therapeutic targets are highly encouraged.
As we enter the third decade of the 21st Century, food allergy continues to be a growing public health concern. To combat this, scientists have successfully developed novel basic and translational animal models to make major advances in the fast-growing field of food allergy. These models are critical to allow scientists to better understand the immunological mechanisms that drive the development of allergic responses to food and develop novel therapeutic strategies for patients suffering from food allergies.
Although key advances have been made to understand how the immune system reacts to mount allergic responses to food, more work needs to be done to define how these immune reactions take place. Immune cells that initially respond to initiate and develop an immunological microenvironment conducive to allow sensitization to a particular food, as well as the antigen presenting cells that activate food allergen-specific T cells, need additional study to better understand the full picture of food-induced immune responses. Whether the immune system mounts a similar response to each type of food allergen (e.g. peanut, shellfish, milk, soy) remains an additional open question. While research in food allergy has made great progress, especially in recent years, much more remains to be learned.
This research topic intends to highlight basic and translational studies in the field of food allergy. The scope of this topic includes work that elucidates immunological mechanisms which contribute to the development of food allergy. We also want to highlight work that describes translational models that work to inhibit, treat, or drive tolerance in food allergy. We are interested in original research articles, reviews, and protocols that offer insight into how food allergy develops and how it could be treated. In vivo mechanistic studies that reveal novel immunological insight into possible therapeutic targets are highly encouraged.