Cancer remains one of the deadliest human diseases worldwide, and is a major threat to human health. Conventional treatment modalities suffer from severe systemic toxicity and unsatisfactory therapeutic outcome. In recent years, with the rapid development of material science and the deepening of tumor biology research, a wide variety of smart drug/gene delivery systems have been developed to achieve concurrent cancer therapy and diagnosis, which will help to overcome the deficiencies of traditional diagnosis and treatment methods. Moreover, researchers designed various multifunctional nanocarriers with desirable physiochemical features for tumor-targeted small molecules or macromolecules (protein, DNA, RNA) delivery.
The heterogeneity of tumor microenvironments poses an enormous obstacle to effective cancer therapy. This Research Topic welcomes submission of Original Research papers, Reviews, Perspective about smart biomaterials and multifunctional nanocarriers for targeted cancer theranostics. These smart delivery systems can effectively modulate tumor microenvironment or intelligently respond to tumor microenvironment (or exogenous stimuli including light, temperature, and magnetic field, etc) , thereby promoting enhanced drug penetration into tumors and exerting more efficient antitumor effect.
The scope of this Research Topic includes, but is not limited to:
(1) Smart inorganic nanomaterials for tumor-targeted drug/gene delivery;
(2) Smart polymeric materials for tumor-targeted drug/gene delivery;
(3) Smart hybrid materials for tumor-targeted drug/gene delivery;
(4) Smart materials for therapeutic protein delivery;
(5) Smart materials for tumor microenvironment modulation;
(6) Smart materials intelligently respond to exogenous stimuli (including light, temperature, and magnetic field) for cancer theranostics.
Cancer remains one of the deadliest human diseases worldwide, and is a major threat to human health. Conventional treatment modalities suffer from severe systemic toxicity and unsatisfactory therapeutic outcome. In recent years, with the rapid development of material science and the deepening of tumor biology research, a wide variety of smart drug/gene delivery systems have been developed to achieve concurrent cancer therapy and diagnosis, which will help to overcome the deficiencies of traditional diagnosis and treatment methods. Moreover, researchers designed various multifunctional nanocarriers with desirable physiochemical features for tumor-targeted small molecules or macromolecules (protein, DNA, RNA) delivery.
The heterogeneity of tumor microenvironments poses an enormous obstacle to effective cancer therapy. This Research Topic welcomes submission of Original Research papers, Reviews, Perspective about smart biomaterials and multifunctional nanocarriers for targeted cancer theranostics. These smart delivery systems can effectively modulate tumor microenvironment or intelligently respond to tumor microenvironment (or exogenous stimuli including light, temperature, and magnetic field, etc) , thereby promoting enhanced drug penetration into tumors and exerting more efficient antitumor effect.
The scope of this Research Topic includes, but is not limited to:
(1) Smart inorganic nanomaterials for tumor-targeted drug/gene delivery;
(2) Smart polymeric materials for tumor-targeted drug/gene delivery;
(3) Smart hybrid materials for tumor-targeted drug/gene delivery;
(4) Smart materials for therapeutic protein delivery;
(5) Smart materials for tumor microenvironment modulation;
(6) Smart materials intelligently respond to exogenous stimuli (including light, temperature, and magnetic field) for cancer theranostics.
