Antibiotics are widely used in many dental procedures, therapeutically or prophylactically. However, not all those uses of antibiotics are supported by evidence. In addition, antimicrobial therapy for bacterial infections should be ideally based on accurate microbiological diagnosis and the results of antimicrobial susceptibility tests.
Currently, microbiological diagnosis and antimicrobial susceptibility tests depend on culture, which has limitations in managing oral and maxillofacial infections. The nature of polymicrobial infections dominated by anaerobes and the presence of uncultivable bacteria request novel molecular approaches to replace the culture-based approach.
The present Research Topic aims to summarize evidence on the risks associated with antimicrobial resistance in oral bacteria. This includes research on evidence-based approaches for the use of antibiotics in dental procedures, molecular mechanisms of antimicrobial resistance in oral bacteria, distribution of resistance genes in the oral microbiome, and novel molecular diagnostic measures for antimicrobial resistance in oral and maxillofacial infections.
The scope of this Research Topic is to investigate the following aspects:
• Evidence-based dentistry for the use of antibiotics in dental procedures
• Molecular mechanisms of antimicrobial resistance of oral bacteria
• Distribution of antimicrobial resistance genes in oral bacteria
• Molecular diagnosis of antimicrobial resistance in oral and maxillofacial infections
The eligible types of articles for this Research Topic include review articles, meta-analyses, opinions, perspectives, and original research articles.
Antibiotics are widely used in many dental procedures, therapeutically or prophylactically. However, not all those uses of antibiotics are supported by evidence. In addition, antimicrobial therapy for bacterial infections should be ideally based on accurate microbiological diagnosis and the results of antimicrobial susceptibility tests.
Currently, microbiological diagnosis and antimicrobial susceptibility tests depend on culture, which has limitations in managing oral and maxillofacial infections. The nature of polymicrobial infections dominated by anaerobes and the presence of uncultivable bacteria request novel molecular approaches to replace the culture-based approach.
The present Research Topic aims to summarize evidence on the risks associated with antimicrobial resistance in oral bacteria. This includes research on evidence-based approaches for the use of antibiotics in dental procedures, molecular mechanisms of antimicrobial resistance in oral bacteria, distribution of resistance genes in the oral microbiome, and novel molecular diagnostic measures for antimicrobial resistance in oral and maxillofacial infections.
The scope of this Research Topic is to investigate the following aspects:
• Evidence-based dentistry for the use of antibiotics in dental procedures
• Molecular mechanisms of antimicrobial resistance of oral bacteria
• Distribution of antimicrobial resistance genes in oral bacteria
• Molecular diagnosis of antimicrobial resistance in oral and maxillofacial infections
The eligible types of articles for this Research Topic include review articles, meta-analyses, opinions, perspectives, and original research articles.