Over the past decade, epitranscriptomics has emerged as an exciting research area focused on post-transcriptional modifications. A series of technological advances have revealed the abundance and location of many biochemical modifications of eukaryotic mRNA, including m6A, 2-Ome and ?, etc. More recent studies have uncovered the mechanisms of RNA modification in microorganisms, such as writing, reading, and erasing of RNA modifications. More importantly, RNA modifications have been found to be involved in significant biological functions, such as regulating growth, development, stress responses, and host-microbe interactions. Advanced high-throughput sequencing and multi-omics analysis provide promising solutions for generating high-resolution blueprints of global modifications and dissecting the biological functions of epitranscriptomics.
This Research Topic aims to provide new insights into the identification and characterization of RNA modifications in microbiology, especially focusing on the interaction between host and pathogen, microbial niche adaptations (for prokaryotic and eukaryotic microbes as well as viruses), and the dynamics and effects of RNA modifications in responses to environmental stresses. Furthermore, novel mechanisms and technical approaches to RNA modifications are highly appreciated for their broad interests.
We welcome the submission of Original Research, Reviews, Mini-reviews, Perspectives, and Commentary Articles on epitranscriptomics in microorganisms that will help us understand the field better. The possible topics may include, but not limited to:
- Studies in all aspects of RNA modification in microorganisms (bacteria, fungi, viruses, protists, etc.)
- New insights into the biological functions of specific RNA modifications
- Novel discoveries of the modification mechanisms of microbial RNA
- Technological advancements in detecting global transcriptome modifications
- Extensive mapping of various RNA modifications across an entire genome of a microorganism
- Studies about elements involved in RNA modification
- Research about the relationship between epitranscriptomics and environmental responses
Over the past decade, epitranscriptomics has emerged as an exciting research area focused on post-transcriptional modifications. A series of technological advances have revealed the abundance and location of many biochemical modifications of eukaryotic mRNA, including m6A, 2-Ome and ?, etc. More recent studies have uncovered the mechanisms of RNA modification in microorganisms, such as writing, reading, and erasing of RNA modifications. More importantly, RNA modifications have been found to be involved in significant biological functions, such as regulating growth, development, stress responses, and host-microbe interactions. Advanced high-throughput sequencing and multi-omics analysis provide promising solutions for generating high-resolution blueprints of global modifications and dissecting the biological functions of epitranscriptomics.
This Research Topic aims to provide new insights into the identification and characterization of RNA modifications in microbiology, especially focusing on the interaction between host and pathogen, microbial niche adaptations (for prokaryotic and eukaryotic microbes as well as viruses), and the dynamics and effects of RNA modifications in responses to environmental stresses. Furthermore, novel mechanisms and technical approaches to RNA modifications are highly appreciated for their broad interests.
We welcome the submission of Original Research, Reviews, Mini-reviews, Perspectives, and Commentary Articles on epitranscriptomics in microorganisms that will help us understand the field better. The possible topics may include, but not limited to:
- Studies in all aspects of RNA modification in microorganisms (bacteria, fungi, viruses, protists, etc.)
- New insights into the biological functions of specific RNA modifications
- Novel discoveries of the modification mechanisms of microbial RNA
- Technological advancements in detecting global transcriptome modifications
- Extensive mapping of various RNA modifications across an entire genome of a microorganism
- Studies about elements involved in RNA modification
- Research about the relationship between epitranscriptomics and environmental responses