It has been demonstrated that new neurons are continuously produced during adulthood in the brain, particularly in the hippocampus of several mammalian species, including humans. Adult neurogenesis has been mostly described in the subventricular zone (SVZ) at the margin of lateral ventricles and in the subgranular zone (SGZ) of the hippocampus. More recently, new neurons have also been discovered in other areas of the adult mammalian brain, including the hypothalamus, striatum, substantia nigra, cortex, and amygdala.
The field of adult neurogenesis has grown rapidly during the last decades. Indeed, adult neurogenesis has been proven critically important for learning and memory, the regulation of emotions, and mental health. It is also a potential therapeutic target for neurodegenerative diseases and neuropsychiatric disorders. Despite recent advances, multiple aspects still need to be addressed for a complete understanding of adult neurogenesis.
In this Research Topic, Frontiers in Neuroscience is looking to address key aspects of adult neurogenesis in order to promote the discussion around this topic and facilitate knowledge dissemination.
We particularly welcome the submission of Original Research, Review, Methods, and Perspective articles on the following sub-topics:
• Contributions that compare adult neurogenesis to early neurogenesis in development - with particular emphasis on the molecular and cellular mechanisms
• The link between the development of new neurons during adulthood and psychological well-being
• The relationship between new memories/learnings and new neurons
• The role of adult neurogenesis in cognitive and behavioral functions
• The necessity of adult neurogenesis in specific neurobiological functions
• Adult neurogenesis as a therapeutical target
• Novel approaches to study the importance of adult neurogenesis
• The effects of anesthesia on adult neurogenesis
• Adult neurogenesis in mammals: interspecies differences and evolutionary trends
It has been demonstrated that new neurons are continuously produced during adulthood in the brain, particularly in the hippocampus of several mammalian species, including humans. Adult neurogenesis has been mostly described in the subventricular zone (SVZ) at the margin of lateral ventricles and in the subgranular zone (SGZ) of the hippocampus. More recently, new neurons have also been discovered in other areas of the adult mammalian brain, including the hypothalamus, striatum, substantia nigra, cortex, and amygdala.
The field of adult neurogenesis has grown rapidly during the last decades. Indeed, adult neurogenesis has been proven critically important for learning and memory, the regulation of emotions, and mental health. It is also a potential therapeutic target for neurodegenerative diseases and neuropsychiatric disorders. Despite recent advances, multiple aspects still need to be addressed for a complete understanding of adult neurogenesis.
In this Research Topic, Frontiers in Neuroscience is looking to address key aspects of adult neurogenesis in order to promote the discussion around this topic and facilitate knowledge dissemination.
We particularly welcome the submission of Original Research, Review, Methods, and Perspective articles on the following sub-topics:
• Contributions that compare adult neurogenesis to early neurogenesis in development - with particular emphasis on the molecular and cellular mechanisms
• The link between the development of new neurons during adulthood and psychological well-being
• The relationship between new memories/learnings and new neurons
• The role of adult neurogenesis in cognitive and behavioral functions
• The necessity of adult neurogenesis in specific neurobiological functions
• Adult neurogenesis as a therapeutical target
• Novel approaches to study the importance of adult neurogenesis
• The effects of anesthesia on adult neurogenesis
• Adult neurogenesis in mammals: interspecies differences and evolutionary trends
