The collective genomes of the gut microbes are regulated by host factors such as health status and dietary structure and closely participate in many physiological processes such as nutrition, metabolism, immunity, and behavioral stress, which play an important role in maintaining body health. Pregnancy is a special stage, during which the hormone level, immune function, and metabolism of the mother's body undergo dramatic changes. Gut microbiota disorder can cause a variety of metabolic and immune diseases, and in recent years, many studies have proved that gut microbiota is inseparable from the regulation of the immune system, nervous system, and hormone secretion in vivo. Changes in the maternal gut microbiota during pregnancy have a profound impact on maternal and fetal health by regulating maternal immunity and metabolism and participating in the occurrence of pregnancy complications such as gestational diabetes mellitus, preeclampsia, and gestational hypertension. However, the short-term and long-term effects of the gut microbiota and its metabolites on maternal and fetal health, as well as the changing trends of the microbiota during pregnancy and its mechanism of action affecting pregnancy outcomes remain unclear, and further studies are needed to clarify and confirm.
Alterations in the gut microbiota can affect maternal physiology, but the role of the relationship in fetal growth remains to be further explored. The main future research direction in this field will take the changing trend of gut microbiota during pregnancy as an important perspective and clarify the role of gut microbiota in the physiological changes of pregnancy and the occurrence and development of complications. In addition, it is necessary to find beneficial microbiota for pregnancy outcomes and explore what changes they have in the adverse pregnancy and then dig into the impact mechanism of these changes, to provide a theoretical basis for preventing complications during pregnancy. It is also worth noting that the timing, species, and dosage of probiotic intervention during pregnancy will also be the focus of future research.
We welcome Original Research, Review, Mini Review, and Perspective articles on themes including, but not limited to:
· The changing trend of gut microbes during pregnancy and its influence on pregnant women.
· Correlation and interaction between pregnancy complications and gut microbes.
· The effect and mechanism of improving gut microbes on pregnancy outcomes.
· The potential relationship between gut microbes and the placenta or fetus.
· Develop or utilize advanced agents or nutrients to improve gut microbial homeostasis during pregnancy.
The collective genomes of the gut microbes are regulated by host factors such as health status and dietary structure and closely participate in many physiological processes such as nutrition, metabolism, immunity, and behavioral stress, which play an important role in maintaining body health. Pregnancy is a special stage, during which the hormone level, immune function, and metabolism of the mother's body undergo dramatic changes. Gut microbiota disorder can cause a variety of metabolic and immune diseases, and in recent years, many studies have proved that gut microbiota is inseparable from the regulation of the immune system, nervous system, and hormone secretion in vivo. Changes in the maternal gut microbiota during pregnancy have a profound impact on maternal and fetal health by regulating maternal immunity and metabolism and participating in the occurrence of pregnancy complications such as gestational diabetes mellitus, preeclampsia, and gestational hypertension. However, the short-term and long-term effects of the gut microbiota and its metabolites on maternal and fetal health, as well as the changing trends of the microbiota during pregnancy and its mechanism of action affecting pregnancy outcomes remain unclear, and further studies are needed to clarify and confirm.
Alterations in the gut microbiota can affect maternal physiology, but the role of the relationship in fetal growth remains to be further explored. The main future research direction in this field will take the changing trend of gut microbiota during pregnancy as an important perspective and clarify the role of gut microbiota in the physiological changes of pregnancy and the occurrence and development of complications. In addition, it is necessary to find beneficial microbiota for pregnancy outcomes and explore what changes they have in the adverse pregnancy and then dig into the impact mechanism of these changes, to provide a theoretical basis for preventing complications during pregnancy. It is also worth noting that the timing, species, and dosage of probiotic intervention during pregnancy will also be the focus of future research.
We welcome Original Research, Review, Mini Review, and Perspective articles on themes including, but not limited to:
· The changing trend of gut microbes during pregnancy and its influence on pregnant women.
· Correlation and interaction between pregnancy complications and gut microbes.
· The effect and mechanism of improving gut microbes on pregnancy outcomes.
· The potential relationship between gut microbes and the placenta or fetus.
· Develop or utilize advanced agents or nutrients to improve gut microbial homeostasis during pregnancy.