Zoonotic viruses continue to pose a serious risk to human and animal health. Of these, negative-sense RNA viruses are recognized as a major threat, being the causative agent of numerous epornitics, epidemics and pandemics. Moreover, the World Health Organization lists numerous negative-sense RNA viruses as priority pathogens of concern due to their pandemic potential and/or lack of adequate countermeasures. Negative-sense RNA viruses such as highly pathogenic avian influenza virus, Hendra and Nipah viruses, Ebola virus, and Crimean-Congo hemorrhagic fever virus, can cause severe disease and devastating infection outcomes in human and animal hosts. Peering through a one health lens, it is crucial to understand infection dynamics in relevant hosts to understand factors that contribute to the emergence, spill over, and disease severity of novel, negative-sense zoonotic RNA viruses.
This research topic aims to provide novel insights into negative-sense RNA virus biology, disease pathogenesis, host-pathogen interactions, and the host response to infection. A fundamental understanding of viral and host factors involved in infection and diseases processes is necessary for for the development of medical countermeasures as well as novel strategies for mitigating the threat of negative-sense RNA viruses.
Submissions of original research, brief research reports, methods, reviews, and mini reviews with a focus on negative-sense RNA viruses are welcomed. Research areas may include:
- Negative-sense RNA viruses of pandemic concern
- Zoonotic negative-sense RNA viruses
- High consequence negative-sense RNA viruses
- Pathogenicity determinants
- Medical countermeasures (vaccines and antivirals)
- Host-pathogens interactions
- Virus characterization
- Host response to infection
- Viral immunology
Zoonotic viruses continue to pose a serious risk to human and animal health. Of these, negative-sense RNA viruses are recognized as a major threat, being the causative agent of numerous epornitics, epidemics and pandemics. Moreover, the World Health Organization lists numerous negative-sense RNA viruses as priority pathogens of concern due to their pandemic potential and/or lack of adequate countermeasures. Negative-sense RNA viruses such as highly pathogenic avian influenza virus, Hendra and Nipah viruses, Ebola virus, and Crimean-Congo hemorrhagic fever virus, can cause severe disease and devastating infection outcomes in human and animal hosts. Peering through a one health lens, it is crucial to understand infection dynamics in relevant hosts to understand factors that contribute to the emergence, spill over, and disease severity of novel, negative-sense zoonotic RNA viruses.
This research topic aims to provide novel insights into negative-sense RNA virus biology, disease pathogenesis, host-pathogen interactions, and the host response to infection. A fundamental understanding of viral and host factors involved in infection and diseases processes is necessary for for the development of medical countermeasures as well as novel strategies for mitigating the threat of negative-sense RNA viruses.
Submissions of original research, brief research reports, methods, reviews, and mini reviews with a focus on negative-sense RNA viruses are welcomed. Research areas may include:
- Negative-sense RNA viruses of pandemic concern
- Zoonotic negative-sense RNA viruses
- High consequence negative-sense RNA viruses
- Pathogenicity determinants
- Medical countermeasures (vaccines and antivirals)
- Host-pathogens interactions
- Virus characterization
- Host response to infection
- Viral immunology