Preeclampsia poses severe risks on both mother and baby during pregnancy. A large body of evidence now indicates that a history of preeclampsia also increases the risk of disease well beyond the index pregnancy. Studies show that mothers are at increased risk of cardiovascular, renal and neurological diseases. Babies are at increased risk of cardiovascular disease, obesity, neurodevelopmental impairments and mental health disorders, across childhood, adolescence and adulthood. There is critical importance in understanding the pathophysiology of these outcomes to uncover appropriate therapeutic targets.
This Research Topic aims to collate basic, translational and applied research that highlight the relationship between preeclampsia and long term adverse outcomes in mother and baby, as well as advances in identifying therapeutic options.
We welcome articles related to:
- developmental origins of health and disease in preeclampsia
- placental insufficiency in preeclampsia
- implications of placental dysfunction in preeclampsia
- organ dysfunction and injury in preeclampsia
- pathophysiological mechanisms of long term outcomes of preeclampsia
- therapeutic targets that improve outcomes during preeclampsia and postpartum, and others.
We encourage submissions from authors from all scientific backgrounds to submit different types of articles to this research topic, particularly original research, reviews and mini-reviews.
Preeclampsia poses severe risks on both mother and baby during pregnancy. A large body of evidence now indicates that a history of preeclampsia also increases the risk of disease well beyond the index pregnancy. Studies show that mothers are at increased risk of cardiovascular, renal and neurological diseases. Babies are at increased risk of cardiovascular disease, obesity, neurodevelopmental impairments and mental health disorders, across childhood, adolescence and adulthood. There is critical importance in understanding the pathophysiology of these outcomes to uncover appropriate therapeutic targets.
This Research Topic aims to collate basic, translational and applied research that highlight the relationship between preeclampsia and long term adverse outcomes in mother and baby, as well as advances in identifying therapeutic options.
We welcome articles related to:
- developmental origins of health and disease in preeclampsia
- placental insufficiency in preeclampsia
- implications of placental dysfunction in preeclampsia
- organ dysfunction and injury in preeclampsia
- pathophysiological mechanisms of long term outcomes of preeclampsia
- therapeutic targets that improve outcomes during preeclampsia and postpartum, and others.
We encourage submissions from authors from all scientific backgrounds to submit different types of articles to this research topic, particularly original research, reviews and mini-reviews.
