Clinical Neuroimmune Biology is a research field that is focused on the molecular and cellular interactions between the nervous and immune systems, and the ensuing pathological processes. The field is critically important in the understanding of the etiology, pathogenesis, and treatment of human neurological diseases. Cytokine research has been one of the major drivers of the field and has undergone major scientific advancements that are likely to have a significant impact on both basic and clinical neurosciences.
The general goal of the Research Topic proposal is to provide an update and critical review of some of the most important advancements in cytokine research as they pertain to neuroscience and cellular pathology, as well as to provide a venue for early and innovative work. A specific goal of the Research Topic is to discuss the role of cytokines in the context of neuro-immune interactions, and their involvement in the diseases of the nervous system. Examination of the therapeutic potential of cytokines as molecular targets as well as pharmaceutical agents will be of particular interest.
The Research Topic will discuss 5 major areas where cytokines are likely to be of interest to basic and clinical neurosciences:
1) dysfunction of the blood-brain barrier
2) mechanisms of myelin diseases (exp. MS, infections, etc.)
3) astrocytopathies (exp. NMO, tumors)
4) autoimmune epilepsies and dementias (exp. NMDA receptor encephalopathies, Alzheimer's disease)
5) Neuro-COVID.
The discussion will be structured and focused on the role of cytokines in the molecular and cellular mechanisms of the diseases, and their potential clinical and therapeutic significance. We particularly welcome submission of Original Research, Review, Methods, and Perspective.
Clinical Neuroimmune Biology is a research field that is focused on the molecular and cellular interactions between the nervous and immune systems, and the ensuing pathological processes. The field is critically important in the understanding of the etiology, pathogenesis, and treatment of human neurological diseases. Cytokine research has been one of the major drivers of the field and has undergone major scientific advancements that are likely to have a significant impact on both basic and clinical neurosciences.
The general goal of the Research Topic proposal is to provide an update and critical review of some of the most important advancements in cytokine research as they pertain to neuroscience and cellular pathology, as well as to provide a venue for early and innovative work. A specific goal of the Research Topic is to discuss the role of cytokines in the context of neuro-immune interactions, and their involvement in the diseases of the nervous system. Examination of the therapeutic potential of cytokines as molecular targets as well as pharmaceutical agents will be of particular interest.
The Research Topic will discuss 5 major areas where cytokines are likely to be of interest to basic and clinical neurosciences:
1) dysfunction of the blood-brain barrier
2) mechanisms of myelin diseases (exp. MS, infections, etc.)
3) astrocytopathies (exp. NMO, tumors)
4) autoimmune epilepsies and dementias (exp. NMDA receptor encephalopathies, Alzheimer's disease)
5) Neuro-COVID.
The discussion will be structured and focused on the role of cytokines in the molecular and cellular mechanisms of the diseases, and their potential clinical and therapeutic significance. We particularly welcome submission of Original Research, Review, Methods, and Perspective.