Translational Research in Severe COVID-19 and Long-Term Symptoms Post-COVID-19

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149

authors

14

articles

Translational Research in Severe COVID-19 and Long-Term Symptoms Post-COVID-19

69.6K

views

149

authors

14

articles

Editorial

27 September 2023

Editorial: Translational research in severe COVID-19 and long-term symptoms post-COVID-19

Vanesa Vicens-Zygmunt

,

Gloria Pérez-Rubio

,

Leslie Chavez-Galan

,

Ivette Buendia-Roldan

and

Ramcés Falfán-Valencia

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Editors

5

Ramcés Falfán-Valencia

National Institute of Respiratory Diseases-Mexico (INER)

Ivette Buendia-Roldan

National Institute of Respiratory Diseases-Mexico (INER)

Vanesa Vicens-Zygmunt

Bellvitge University Hospital

Leslie Chavez-Galan

National Institute of Respiratory Diseases-Mexico (INER)

Gloria Pérez-Rubio

Laboratorio de HLA, Instituto Nacional de Enfermedades Respiratorias-México (INER)

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About

Many patients with COVID-19 suffer long-term symptoms, breathlessness, pain, “brain fog,” trouble sleeping, headaches, fatigue, chronic cough, depression, and anxiety that linger or appear more than four weeks after initial infection, whether hospitalized or not. The symptoms can be severe enough to interfere with work and daily tasks and are persistent for more than 12 weeks. Currently, the criteria for diagnosing “long COVID” is unclear due to its varying symptoms and pathophysiology. Emerging evidence suggests that long COVID is caused by the immune and inflammatory responses in many severe acute viral infections. Possible explanations include a hidden reservoir of SARS-CoV-2, a misfiring immune system, or a metabolic problem triggered by the infection.

By some estimates, 10% to 30% of COVID-19 patients develop long COVID-19. Also, early data suggest potentially severe long-term consequences of COVID-19 are the development of long COVID-19-related interstitial lung manifestations.

Given the need to develop additional knowledge in this field, in this collection, we aim to address the role of molecular, biochemical, genetic/genomic, and immunological factors contributing to clinical manifestations in long COVID-19 to identify target markers in therapeutics and rehabilitation in affected subjects.

We welcome original translational research and review papers contributing to novel information on the relationship between long COVID-19 and molecular, biochemical, microbiome (co-infection and interaction with other microorganisms), and clinical (including those epidemiological and image studies) research.

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Editors

Ramcés Falfán-Valencia

National Institute of Respiratory Diseases-Mexico (INER)

Ivette Buendia-Roldan

National Institute of Respiratory Diseases-Mexico (INER)

Vanesa Vicens-Zygmunt

Bellvitge University Hospital

Leslie Chavez-Galan

National Institute of Respiratory Diseases-Mexico (INER)

Gloria Pérez-Rubio

Laboratorio de HLA, Instituto Nacional de Enfermedades Respiratorias-México (INER)

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Published In

Frontiers in Medicine

Infectious Diseases: Pathogenesis and Therapy

Frontiers in Public Health

Infectious Diseases: Epidemiology and Prevention

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