Aquaculture, as one of the fastest-growing sources of high-quality proteins, contributes significantly to world food security. Disease prevention and control are indispensable for the healthy and sustainable aquaculture industry. Vaccination has been one of the most effective methods to control the emerging and re-emerging infectious diseases in aquaculture. Moreover, aquatic vaccines have shown potential beneficial effects on human health by overcoming the negative effects due to the abuse of pharmaceuticals and antibiotics, as well as their residues in food and the environment. From the perspective of sustainable and prosperous aquaculture, vaccination has been considered a crucial part of comprehensive fish health management.
In recent decades, scientific and technological advances have paved newer paths in both basic and applied research areas of aquatic vaccines. Efforts in new technologies, approaches, and strategies have been devoted to developing and designing novel aquatic vaccines with higher quality and efficiency. Reverse vaccinology and structural vaccinology were also employed to screen stronger antigens and develop the immunomics-based vaccines and computer-aided vaccines; Genetic engineering recombinant and chemical methods were applied to design the adjuvant-vaccines, polyvalent and combination vaccines, nanoparticle-based vaccines/nano vaccines and targeted vaccines. Meanwhile, novel insights also have been proposed to reveal the immunoprotective mechanism of aquatic vaccines and enrich the knowledge of immune response mechanisms including mucosal immunity and systemic immunity in aquatic species.
This research topic is aiming to comprehensively discuss recent advances in the utilization of novel technologies, approaches, and strategies in improving the immunoprotection of aquatic vaccines, as well as to bring novel insights into the vaccines’ immunoprotective mechanism and the immune response mechanism in aquatic vertebrate and invertebrate species. We hope this research topic could replenish the knowledge of fish immune system and immune response mechanism and accelerate the vaccine development and application in the aquaculture industry.
We welcome the submission of Original Research, Review articles, and Mini-Reviews, which include, but are not limited to, the following sub-topics:
(1) Novel technologies to design and develop aquatic vaccines, such as immunomics-based vaccines, computer-aided vaccines, etc.
(2) Novel strategies to improve the immunoprotection of aquatic vaccines, such as adjuvant vaccines, polyvalent and combination vaccines, etc.
(3) Novel insights to demonstrate the immunoprotective mechanism induced by different vaccination routes including oral, injection, immersion vaccination, etc.
(4) Demonstrating the mechanism and connection of mucosal immunity and systemic immunity induced by immersion vaccines in aquatic species.
(5) The innate immunity and adaptive immunity, humoral immunity and cellular immunity induced by different vaccination routes in aquatic species.
(6) The regulation of immune-related genes and signaling pathways after vaccination in aquatic species.
(7) The effect of vaccines on the host health and intestinal microbiome in aquatic species.
(8) The pathogen survival strategies including immune escape and adaptive evolution after vaccination in aquatic species.
(9) The host immune memory induced by different vaccination routes in aquatic species.
(10) The side effects such as inflammation caused by vaccination in aquatic species.
Aquaculture, as one of the fastest-growing sources of high-quality proteins, contributes significantly to world food security. Disease prevention and control are indispensable for the healthy and sustainable aquaculture industry. Vaccination has been one of the most effective methods to control the emerging and re-emerging infectious diseases in aquaculture. Moreover, aquatic vaccines have shown potential beneficial effects on human health by overcoming the negative effects due to the abuse of pharmaceuticals and antibiotics, as well as their residues in food and the environment. From the perspective of sustainable and prosperous aquaculture, vaccination has been considered a crucial part of comprehensive fish health management.
In recent decades, scientific and technological advances have paved newer paths in both basic and applied research areas of aquatic vaccines. Efforts in new technologies, approaches, and strategies have been devoted to developing and designing novel aquatic vaccines with higher quality and efficiency. Reverse vaccinology and structural vaccinology were also employed to screen stronger antigens and develop the immunomics-based vaccines and computer-aided vaccines; Genetic engineering recombinant and chemical methods were applied to design the adjuvant-vaccines, polyvalent and combination vaccines, nanoparticle-based vaccines/nano vaccines and targeted vaccines. Meanwhile, novel insights also have been proposed to reveal the immunoprotective mechanism of aquatic vaccines and enrich the knowledge of immune response mechanisms including mucosal immunity and systemic immunity in aquatic species.
This research topic is aiming to comprehensively discuss recent advances in the utilization of novel technologies, approaches, and strategies in improving the immunoprotection of aquatic vaccines, as well as to bring novel insights into the vaccines’ immunoprotective mechanism and the immune response mechanism in aquatic vertebrate and invertebrate species. We hope this research topic could replenish the knowledge of fish immune system and immune response mechanism and accelerate the vaccine development and application in the aquaculture industry.
We welcome the submission of Original Research, Review articles, and Mini-Reviews, which include, but are not limited to, the following sub-topics:
(1) Novel technologies to design and develop aquatic vaccines, such as immunomics-based vaccines, computer-aided vaccines, etc.
(2) Novel strategies to improve the immunoprotection of aquatic vaccines, such as adjuvant vaccines, polyvalent and combination vaccines, etc.
(3) Novel insights to demonstrate the immunoprotective mechanism induced by different vaccination routes including oral, injection, immersion vaccination, etc.
(4) Demonstrating the mechanism and connection of mucosal immunity and systemic immunity induced by immersion vaccines in aquatic species.
(5) The innate immunity and adaptive immunity, humoral immunity and cellular immunity induced by different vaccination routes in aquatic species.
(6) The regulation of immune-related genes and signaling pathways after vaccination in aquatic species.
(7) The effect of vaccines on the host health and intestinal microbiome in aquatic species.
(8) The pathogen survival strategies including immune escape and adaptive evolution after vaccination in aquatic species.
(9) The host immune memory induced by different vaccination routes in aquatic species.
(10) The side effects such as inflammation caused by vaccination in aquatic species.
