Globally, chronic inflammation-related diseases are the leading cause of death, including cardiovascular disease, cancer, diabetes mellitus, nonalcoholic fatty liver disease, and autoimmune and neurodegenerative diseases. Chronic inflammatory disease is a low-grade continuous inflammation that may cause tissue and organ damage through oxidative stress et al. Typical biomarkers and medicine for chronic inflammatory diseases need further development. Traditional medicine had its traditional ways of healing illnesses, such as moxibustion, and Chinese herbal medicine in Chinese medicine. Although traditional medicine has curative effects in the treatment of chronic inflammatory diseases, a pharmacological mechanism based on targets and pathways is not yet clear, and effective components of herbal medicine are not identified clearly.
Traditional medicine has a long history in the treatment of chronic inflammatory diseases, but most of its pharmacological mechanisms remain unclear. This Research Topic focuses on traditional medicine for chronic inflammatory disease. Herbal medicine and indigenous medical techniques were encouraged to explore the novel pharmacological mechanism according to the traditional application by various omics technology and epigenetics. The pharmacological mechanism of bioactive metabolites in herbal medicine could be identified by experimental methods at the animal level or a combination of theoretical and experimental methods. Studies on pharmacological activity of highly purified, chemically well-characterized plant or fungal metabolites will also be considered. Whenever crude extracts and/or mixtures are used, quality control of non-market herbal materials should be carried out by HPLC or HPLC-MS to ensure replicability (and/or previously published). Producer and batch number for herbal materials sold on the market should be provided.
The present Topic welcomes high-quality Original Research as well as Review articles focusing on traditional medicine and chronic inflammatory diseases. Clinical trials will not be considered for review. We particularly welcome studies that embraces the multidisciplinary effort in (but not limited to) the following topics:
• Investigations of the underlying pharmacological mechanism of action of herbal medicine and indigenous medical techniques for the treatment of chronic inflammatory disease.
• Discovery of active metabolites of herbal medicines for the treatment of chronic inflammatory disease
• Identification of potential targets of disease-associated proteins identified by network approach if these are combined with a detailed (in vitro or in vivo) pharmacological evaluation.
•Systematic and critical reviews of traditional herbal medicines and medical techniques relevant for Chronic Inflammatory Disease.
Globally, chronic inflammation-related diseases are the leading cause of death, including cardiovascular disease, cancer, diabetes mellitus, nonalcoholic fatty liver disease, and autoimmune and neurodegenerative diseases. Chronic inflammatory disease is a low-grade continuous inflammation that may cause tissue and organ damage through oxidative stress et al. Typical biomarkers and medicine for chronic inflammatory diseases need further development. Traditional medicine had its traditional ways of healing illnesses, such as moxibustion, and Chinese herbal medicine in Chinese medicine. Although traditional medicine has curative effects in the treatment of chronic inflammatory diseases, a pharmacological mechanism based on targets and pathways is not yet clear, and effective components of herbal medicine are not identified clearly.
Traditional medicine has a long history in the treatment of chronic inflammatory diseases, but most of its pharmacological mechanisms remain unclear. This Research Topic focuses on traditional medicine for chronic inflammatory disease. Herbal medicine and indigenous medical techniques were encouraged to explore the novel pharmacological mechanism according to the traditional application by various omics technology and epigenetics. The pharmacological mechanism of bioactive metabolites in herbal medicine could be identified by experimental methods at the animal level or a combination of theoretical and experimental methods. Studies on pharmacological activity of highly purified, chemically well-characterized plant or fungal metabolites will also be considered. Whenever crude extracts and/or mixtures are used, quality control of non-market herbal materials should be carried out by HPLC or HPLC-MS to ensure replicability (and/or previously published). Producer and batch number for herbal materials sold on the market should be provided.
The present Topic welcomes high-quality Original Research as well as Review articles focusing on traditional medicine and chronic inflammatory diseases. Clinical trials will not be considered for review. We particularly welcome studies that embraces the multidisciplinary effort in (but not limited to) the following topics:
• Investigations of the underlying pharmacological mechanism of action of herbal medicine and indigenous medical techniques for the treatment of chronic inflammatory disease.
• Discovery of active metabolites of herbal medicines for the treatment of chronic inflammatory disease
• Identification of potential targets of disease-associated proteins identified by network approach if these are combined with a detailed (in vitro or in vivo) pharmacological evaluation.
•Systematic and critical reviews of traditional herbal medicines and medical techniques relevant for Chronic Inflammatory Disease.