Clinical Nutrition and Oncologic Outcomes, volume II

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Paula Ravasco

Catholic University of Portugal

Antti Mäkitie

University of Helsinki

Faith Ottery

Ottery & Associates, LLC

Kalliopi-Anna Poulia

Agricultural University of Athens

Lucio Lara Santos

Portuguese Institute of Oncology Francisco Gentil

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This collection is a continuation of the 'Volume I' Clinical Nutrition and Oncologic Outcomes .

Nutritional wasting is highly prevalent in cancer patients and impacts their survival and overall prognosis post anti-neoplastic treatments and interventions. Tolerance and efficacy of treatment regimens and outcome of anti-neoplastic treatments, depend on several aspects, one of the most important is nutritional status. Weight loss occurs early in the course of disease and may develop at any time throughout the patient’ journey. Patients at particularly high risk of malnutrition include those with cancer of the head-and-neck, upper gastrointestinal, and lung cancer. Malnutrition has a negative impact on outcomes and survival, including impaired quality of life, higher surgical complications, prolonged length of stay, and increased treatment toxicity, poorer compliance, and decreased response.

Adequate nutritional therapy can contribute to maintaining or ameliorating nutritional and functional status, in turn associated with better tolerability of anticancer treatment and improved prognosis. Historically, treatment advances in cancer have predominantly focused on the introduction of new substances. The increased and prolonged use of such regimens may expose the patient to the prolonged risk of nutritional impairment and progressive depletion of body stores. Counteracting such depletion with nutrition represents a major adjuvant goal in modern oncology, as a deteriorated nutritional status or a high risk of malnutrition is a key prognostic factor for later treatment success or failure.

This Volume II of the Research Topic Clinical Nutrition and Oncologic Outcomes, welcomes novel multidisciplinary research aimed to understand optimal nutrition interventions to revert, prevent and treat nutritional wasting in different cancer types. We welcome studies on interventions to promote anabolism and stop catabolism, and also to optimise body composition and modulate treatment associated dose limiting toxicity. We also aim to receive studies on adjuvant nutrition intervention to improve oncologic treatment tolerance and efficacy. Survival and quality of life are mandatory outcomes that we wish to focus on with this topic.

We again welcome original studies and systematic reviews of the literature on themes such as but not limited to:

• Research on nutritional status, body composition, clinical, physical and biochemical parameters and their evolution throughout the disease course of different cancers
• Nutritional interventions, their efficacy and their impact on patient outcomes
• Metabolic and nutritional alterations that influence patient recovery and survival outcomes
• Intervention studies on Tailored nutritional interventions
• Multimodal interventions and outcomes
• Dose limiting toxicity
• Randomised Controlled studies
• Analytical, descriptive and cross-sectional studies
• Systematic reviews and meta-analyses

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Editors

Paula Ravasco

Catholic University of Portugal

Antti Mäkitie

University of Helsinki

Faith Ottery

Ottery & Associates, LLC

Kalliopi-Anna Poulia

Agricultural University of Athens

Lucio Lara Santos

Portuguese Institute of Oncology Francisco Gentil

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Frontiers in Nutrition

Clinical Nutrition

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