Glioma is the most common intracranial malignant tumor. Despite the past few decades witnessing developments in neurosurgery, chemotherapy, and radiotherapy, the overall survival of glioma remains far away from what patients expect. Moreover, glioma recurs with a high probability and most recurrences appear in or near the resection cavity. Therefore, the maximal-safe resection of glioma is the mainstay pursuit of surgical operations for neurosurgeons around the world. Recently, a variety of novel technologies have been developed to help neurosurgeons achieve the maximal-safe resection of glioma. Molecular marker imaging of the extent of glioma invasion is a good complement to surgical resection at the microscopic level. However, molecular boundary definition and navigation are still hot issues that have been widely discussed. Meanwhile, modified microsurgery with the assistance of endoscopy is rapidly developing, which contributed to the solution of midline diffuse gliomas resection. Additionally, some mini-invasive approaches like stereotactic thermal ablation provided more options to treat glioma surgically. All these advancements broaden our knowledge of glioma surgery. Therefore, we need more rigorous clinical evidence to verify the effectiveness of these emerging technologies and appeal to more innovative surgical approaches.
In this Research Topic, we would like to invite neurosurgeons and scientists to share their experience in the scope of image-guided surgery, minimally invasive surgery, innovative surgical methods or instruments, and molecular visualized surgery, which showcase advances in surgical approaches for the treatment of glioma, especially in addressing several unresolved problems in glioma surgery, like real-time brain shift correction, molecular boundary definition, the surgical corridor for deep-seated tumor and non-invasive cortical stimulation, etc. Bringing in special clinical experiences, new surgical strategies, novel intra-operative technologies and original anatomic findings from different hospitals, institutes, and countries around the world can benefit both neurosurgeons and patients.
We welcome submissions of Original Research and Review articles focusing on surgical approaches for the treatment of glioma including:
• Image-guide surgery
• Anatomic essentials in minimally invasive surgery
• Innovative surgical methods or instruments
• Molecular visualized surgery
• Real-time brain shift correction
• Molecular boundary definition
• Surgical corridor for deep-seated tumor
• Non-invasive cortical stimulation
• Novel technologies performed in the surgical treatments of glioma are welcome
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Glioma is the most common intracranial malignant tumor. Despite the past few decades witnessing developments in neurosurgery, chemotherapy, and radiotherapy, the overall survival of glioma remains far away from what patients expect. Moreover, glioma recurs with a high probability and most recurrences appear in or near the resection cavity. Therefore, the maximal-safe resection of glioma is the mainstay pursuit of surgical operations for neurosurgeons around the world. Recently, a variety of novel technologies have been developed to help neurosurgeons achieve the maximal-safe resection of glioma. Molecular marker imaging of the extent of glioma invasion is a good complement to surgical resection at the microscopic level. However, molecular boundary definition and navigation are still hot issues that have been widely discussed. Meanwhile, modified microsurgery with the assistance of endoscopy is rapidly developing, which contributed to the solution of midline diffuse gliomas resection. Additionally, some mini-invasive approaches like stereotactic thermal ablation provided more options to treat glioma surgically. All these advancements broaden our knowledge of glioma surgery. Therefore, we need more rigorous clinical evidence to verify the effectiveness of these emerging technologies and appeal to more innovative surgical approaches.
In this Research Topic, we would like to invite neurosurgeons and scientists to share their experience in the scope of image-guided surgery, minimally invasive surgery, innovative surgical methods or instruments, and molecular visualized surgery, which showcase advances in surgical approaches for the treatment of glioma, especially in addressing several unresolved problems in glioma surgery, like real-time brain shift correction, molecular boundary definition, the surgical corridor for deep-seated tumor and non-invasive cortical stimulation, etc. Bringing in special clinical experiences, new surgical strategies, novel intra-operative technologies and original anatomic findings from different hospitals, institutes, and countries around the world can benefit both neurosurgeons and patients.
We welcome submissions of Original Research and Review articles focusing on surgical approaches for the treatment of glioma including:
• Image-guide surgery
• Anatomic essentials in minimally invasive surgery
• Innovative surgical methods or instruments
• Molecular visualized surgery
• Real-time brain shift correction
• Molecular boundary definition
• Surgical corridor for deep-seated tumor
• Non-invasive cortical stimulation
• Novel technologies performed in the surgical treatments of glioma are welcome
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.