Homology of medicine and food materials play important roles in health protection and disease around the world. Phytochemical studies have revealed the categories and structures of the food-sourced medicinal constituents, including polysaccharides, flavones, anthraquinones, phenylpropanoids, alkaloids, and saponins. These constituents have been used to improve immunity, protect the liver, modulate the gut microbiota, treat inflammations, protect the heart and brain, and cure cancers. Thus, studying the pharmacological effects of the constituents of the homology of medicines and foods is of great importance in the medical industry, food industry, and stockbreeding.
Homology of medicine and food materials and their metabolites have shown nutritional immunological activities on immune cells and organs. They not only stimulate or depress the effects of several immune cells like RAW 264.7, dendritic cells, and lymphocyte, but also modulate intestinal and lung barrier function, as well as mucosal immune of the respiratory and digestive tract, gut microbiota, inflammatory responses, and tumor immune. These effects are adjusted and controlled through various pathways, such as NF-?B/MAPK and PI3K/AKT/mTOR. However, more immunological effects and pathways should be studied.
This Research Topic aims to find more nutritional immunological effects of the constituents from the homology of medicine and food materials by using pharmacological methods in vitro and in vivo. Furthermore, the mechanisms of these activities are also elucidated via molecular biological methods.
• The structural elucidations of the homology of medicine and food constituents and their nutritional immunological effects and the mechanisms;
• Network pharmacology and Multi-omics studies on the nutritional immunological effects and the mechanisms of the homology of medicine and food constituents;
• Gut-lung axis, gut-liver axis, gut-brain axis, gut-kidney axis, and nutritional immunology studies on the homology of medicine and food constituents;
• Nutritional immunological response by the homology of medicine and food constituents to the environmental risk factors;
• New models that established to investigate the nutritional immunological effects.
Homology of medicine and food materials play important roles in health protection and disease around the world. Phytochemical studies have revealed the categories and structures of the food-sourced medicinal constituents, including polysaccharides, flavones, anthraquinones, phenylpropanoids, alkaloids, and saponins. These constituents have been used to improve immunity, protect the liver, modulate the gut microbiota, treat inflammations, protect the heart and brain, and cure cancers. Thus, studying the pharmacological effects of the constituents of the homology of medicines and foods is of great importance in the medical industry, food industry, and stockbreeding.
Homology of medicine and food materials and their metabolites have shown nutritional immunological activities on immune cells and organs. They not only stimulate or depress the effects of several immune cells like RAW 264.7, dendritic cells, and lymphocyte, but also modulate intestinal and lung barrier function, as well as mucosal immune of the respiratory and digestive tract, gut microbiota, inflammatory responses, and tumor immune. These effects are adjusted and controlled through various pathways, such as NF-?B/MAPK and PI3K/AKT/mTOR. However, more immunological effects and pathways should be studied.
This Research Topic aims to find more nutritional immunological effects of the constituents from the homology of medicine and food materials by using pharmacological methods in vitro and in vivo. Furthermore, the mechanisms of these activities are also elucidated via molecular biological methods.
• The structural elucidations of the homology of medicine and food constituents and their nutritional immunological effects and the mechanisms;
• Network pharmacology and Multi-omics studies on the nutritional immunological effects and the mechanisms of the homology of medicine and food constituents;
• Gut-lung axis, gut-liver axis, gut-brain axis, gut-kidney axis, and nutritional immunology studies on the homology of medicine and food constituents;
• Nutritional immunological response by the homology of medicine and food constituents to the environmental risk factors;
• New models that established to investigate the nutritional immunological effects.
