Fighting disease is the eternal theme of human beings, and the diagnosis of disease is an indispensable part of it. As the understanding of disease goes down to the molecular level, it is known that abnormal states of disease can lead to the up- or down-regulation of various measurable biomarkers. Targeted construction of biosensing principles, methods and technologies for rapid, sensitive, and specific qualitative and quantitative analysis of these disease biomarkers has been playing a critical role in disease prevention, early diagnosis, and prognosis evaluation. In recent decades, optical biosensing, which can display biological recognition and information extraction through optical signal changes with the advantages of high sensitivity, high speed and high-throughput detection, has received extensive attention and has been widely used in clinical testing. Furthermore, the combination of optical biosensing with the increasingly emerging technologies of material science, optics and electronics has accelerated its development in biomarker analysis.
This research topic focuses on the recent advances in disease biomarker analysis based on optical biosensing. Specifically, it covers the latest advances in all aspects of the development and application of optical biosensing principles, methods and technologies for disease biomarker analysis. The analytical object not only include various biological substances, such as proteins, nucleic acids, glycoconjugates and other small molecules, but also include a variety of emerging biomarkers, such as exosomes, circulating tumor DNA, and circulating tumor cells, etc., and also include complex samples or sample systems, such as genomics, proteomics, transcriptomics, etc. The methodologies cover spectral analysis, imaging analysis, optical biosensors, and portable optical detection equipment/platforms. The topic editors hope to promote communications between researchers from different research directions, and to promote the development of related fields.
We welcome authors to submit Original Research articles, Reviews, and Perspectives on the following themes that include, but are not limited to:
• Development of principles and designs of optical biosensing methods;
• Development of various optical biosensing technologies in the analysis of disease biomarkers;
• Functionalized optical biosensors combined with new materials and new technologies;
• Application of optical biosensing methods for clinical analysis of disease biomarkers;
• Exploration of new disease markers by using optical biosensing techniques.
Fighting disease is the eternal theme of human beings, and the diagnosis of disease is an indispensable part of it. As the understanding of disease goes down to the molecular level, it is known that abnormal states of disease can lead to the up- or down-regulation of various measurable biomarkers. Targeted construction of biosensing principles, methods and technologies for rapid, sensitive, and specific qualitative and quantitative analysis of these disease biomarkers has been playing a critical role in disease prevention, early diagnosis, and prognosis evaluation. In recent decades, optical biosensing, which can display biological recognition and information extraction through optical signal changes with the advantages of high sensitivity, high speed and high-throughput detection, has received extensive attention and has been widely used in clinical testing. Furthermore, the combination of optical biosensing with the increasingly emerging technologies of material science, optics and electronics has accelerated its development in biomarker analysis.
This research topic focuses on the recent advances in disease biomarker analysis based on optical biosensing. Specifically, it covers the latest advances in all aspects of the development and application of optical biosensing principles, methods and technologies for disease biomarker analysis. The analytical object not only include various biological substances, such as proteins, nucleic acids, glycoconjugates and other small molecules, but also include a variety of emerging biomarkers, such as exosomes, circulating tumor DNA, and circulating tumor cells, etc., and also include complex samples or sample systems, such as genomics, proteomics, transcriptomics, etc. The methodologies cover spectral analysis, imaging analysis, optical biosensors, and portable optical detection equipment/platforms. The topic editors hope to promote communications between researchers from different research directions, and to promote the development of related fields.
We welcome authors to submit Original Research articles, Reviews, and Perspectives on the following themes that include, but are not limited to:
• Development of principles and designs of optical biosensing methods;
• Development of various optical biosensing technologies in the analysis of disease biomarkers;
• Functionalized optical biosensors combined with new materials and new technologies;
• Application of optical biosensing methods for clinical analysis of disease biomarkers;
• Exploration of new disease markers by using optical biosensing techniques.
