Atherosclerosis is a systemic disease and the common cause of heart attacks, strokes and peripheral vascular disease collectively referred to as cardiovascular diseases (CVD), which are the leading cause of global mortality and a major contributor to disability and rising health care costs. The global number of total CVD nearly doubled from 271 million in 1990 to 523 million in 2019, and the number of CVD deaths steadily increased from 12.1 million in 1990, reaching 18.6 million in 2019. By 2030, approximately 23.6 million people are predicted to die from CVD annually. The huge and still growing burden of CVD on individuals, families, and health-care systems indicates an urgent need for prevention and treatment measures on atherosclerotic diseases. Preventing severe atherosclerosis progression is expected to decrease high cardiovascular event rate.
However, there still exist challenges to be addressed. These challenges include but are not limited to 1) early detect participants with high-risk of CVD; 2) identify novel indicators for progression and prognosis of atherosclerotic diseases; 3) comorbidities of atherosclerotic diseases; 4) new drugs and therapies on atherosclerosis and CVD.
In this research topic, we would like to create a forum for high-quality epidemiology and clinical researches in the field of atherosclerosis and CVD, via collaboration from a number of professional disciplines such as clinical medicine, nursing, and/or public health. Implications from this topic will focus on guiding comprehensive care and best practice in preventing and managing major atherosclerotic CVD, including coronary heart disease, stroke, and peripheral vascular disease, and other chronic diseases which are associated with atherosclerosis, such as hypertension, diabetes, chronic kidney disease, and dementia.
This topic welcomes a wide variety of researches in atherosclerosis and CVD, including community-based and hospital-based observational studies, interventional studies (such as RCTs), and systematic reviews and meta-analyses, but not fundamental researches, intend to provide novel insights towards preventing and managing atherosclerotic CVD, including coronary heart disease, stroke, and peripheral vascular disease, and other chronic diseases which are associated with atherosclerosis, such as hypertension, diabetes, chronic kidney disease, and dementia. Studies on the following topics will be of special interest:
• Disease burden of atherosclerotic CVD and comorbidities in the general populations, as well as attributable risk factors
• Prediction models of incident atherosclerotic CVD and comorbidities in the general populations
• Prognostic models of recurrent CVD and other outcomes (such as all-cause death, CKD, and dementia) in patients with atherosclerotic diseases
• Identifying novel biomarkers for atherosclerosis progression and regression
• Exploring effective interventions including health education, lifestyle intervention, new drugs, and new therapies on atherosclerosis, CVD, and other chronic diseases which are associated with atherosclerosis
Atherosclerosis is a systemic disease and the common cause of heart attacks, strokes and peripheral vascular disease collectively referred to as cardiovascular diseases (CVD), which are the leading cause of global mortality and a major contributor to disability and rising health care costs. The global number of total CVD nearly doubled from 271 million in 1990 to 523 million in 2019, and the number of CVD deaths steadily increased from 12.1 million in 1990, reaching 18.6 million in 2019. By 2030, approximately 23.6 million people are predicted to die from CVD annually. The huge and still growing burden of CVD on individuals, families, and health-care systems indicates an urgent need for prevention and treatment measures on atherosclerotic diseases. Preventing severe atherosclerosis progression is expected to decrease high cardiovascular event rate.
However, there still exist challenges to be addressed. These challenges include but are not limited to 1) early detect participants with high-risk of CVD; 2) identify novel indicators for progression and prognosis of atherosclerotic diseases; 3) comorbidities of atherosclerotic diseases; 4) new drugs and therapies on atherosclerosis and CVD.
In this research topic, we would like to create a forum for high-quality epidemiology and clinical researches in the field of atherosclerosis and CVD, via collaboration from a number of professional disciplines such as clinical medicine, nursing, and/or public health. Implications from this topic will focus on guiding comprehensive care and best practice in preventing and managing major atherosclerotic CVD, including coronary heart disease, stroke, and peripheral vascular disease, and other chronic diseases which are associated with atherosclerosis, such as hypertension, diabetes, chronic kidney disease, and dementia.
This topic welcomes a wide variety of researches in atherosclerosis and CVD, including community-based and hospital-based observational studies, interventional studies (such as RCTs), and systematic reviews and meta-analyses, but not fundamental researches, intend to provide novel insights towards preventing and managing atherosclerotic CVD, including coronary heart disease, stroke, and peripheral vascular disease, and other chronic diseases which are associated with atherosclerosis, such as hypertension, diabetes, chronic kidney disease, and dementia. Studies on the following topics will be of special interest:
• Disease burden of atherosclerotic CVD and comorbidities in the general populations, as well as attributable risk factors
• Prediction models of incident atherosclerotic CVD and comorbidities in the general populations
• Prognostic models of recurrent CVD and other outcomes (such as all-cause death, CKD, and dementia) in patients with atherosclerotic diseases
• Identifying novel biomarkers for atherosclerosis progression and regression
• Exploring effective interventions including health education, lifestyle intervention, new drugs, and new therapies on atherosclerosis, CVD, and other chronic diseases which are associated with atherosclerosis
