Endocrinology has traditionally involved description and mechanistic analysis of function and action of individual hormones. This approach has produced a rich body of knowledge, but also revealed several deficiencies. First, most hormones have pleiotropic actions which may vary based on the organism’s developmental stage or the temporal pattern of hormone release. And second, a number of different hormones may interact to cooperatively affect specific body structures and physiology. An alternative to focussing on the function and actions of individual hormones is to focus, instead, on the structural and physiological endpoints they influence. The alternative approach, is particularly relevant to the exercise-induced hormone secretion and actions It will be pursued in the Integrative Exercise Endocrinology topic, which also, has traditionally suffered from the single-hormone focus. Movement is a fundamental property of most animals as it evolved to respond to environmental, physiological, chrono-biological, and psychological variables. In humans, it can increase energy metabolism by 5 to 15 times the resting rate to provide energy for muscle contraction. But also, in conjunction with changes in energy availability, it can either stimulate or suppress growth and fertility as well as affect differentially a number of other body endpoints including body composition, structure, and mass. These will be the themes for papers sought for this topic as they address the effects of exercise-induced hormone secretion and action on human physiology and structure.
The following themes are being sought:
• The antidiabetic effects of exercise capacity of exercise to increase insulin sensitivity via endocrine and non-endocrine enzymatic mechanisms.
• Exercise counteracting estrogenic decline on bone mineral after menopause and contributing to its decline in excessive exercise
• Exercise affects physiology by inter-organ signalling via cytokine messengers from the muscle, liver and adipose tissues.
• Genetic and epigenetic induction of growth factors by exercise eliciting IGF messengers in target organs.
• Exercise affecting fertility and growth through changes in hormone pulsatility
• Effect of exercise on cognitive function via brain-derived brain factor (BDNF) and cytokines
• Exercise role in the management of body mass through endocrine control of metabolism
Endocrinology has traditionally involved description and mechanistic analysis of function and action of individual hormones. This approach has produced a rich body of knowledge, but also revealed several deficiencies. First, most hormones have pleiotropic actions which may vary based on the organism’s developmental stage or the temporal pattern of hormone release. And second, a number of different hormones may interact to cooperatively affect specific body structures and physiology. An alternative to focussing on the function and actions of individual hormones is to focus, instead, on the structural and physiological endpoints they influence. The alternative approach, is particularly relevant to the exercise-induced hormone secretion and actions It will be pursued in the Integrative Exercise Endocrinology topic, which also, has traditionally suffered from the single-hormone focus. Movement is a fundamental property of most animals as it evolved to respond to environmental, physiological, chrono-biological, and psychological variables. In humans, it can increase energy metabolism by 5 to 15 times the resting rate to provide energy for muscle contraction. But also, in conjunction with changes in energy availability, it can either stimulate or suppress growth and fertility as well as affect differentially a number of other body endpoints including body composition, structure, and mass. These will be the themes for papers sought for this topic as they address the effects of exercise-induced hormone secretion and action on human physiology and structure.
The following themes are being sought:
• The antidiabetic effects of exercise capacity of exercise to increase insulin sensitivity via endocrine and non-endocrine enzymatic mechanisms.
• Exercise counteracting estrogenic decline on bone mineral after menopause and contributing to its decline in excessive exercise
• Exercise affects physiology by inter-organ signalling via cytokine messengers from the muscle, liver and adipose tissues.
• Genetic and epigenetic induction of growth factors by exercise eliciting IGF messengers in target organs.
• Exercise affecting fertility and growth through changes in hormone pulsatility
• Effect of exercise on cognitive function via brain-derived brain factor (BDNF) and cytokines
• Exercise role in the management of body mass through endocrine control of metabolism