Candida auris, a multidrug resistant fungal pathogen, which was first identified a decade ago, has been reported in many countries and continents globally. Since then, it has been associated with many outbreaks in hospitals and nursing homes as it can spread easily between patients. Furthermore, C. auris can persist for weeks on inanimate surfaces and medical equipment largely due to its limited sensitivity to non-sporicidal disinfectants. It can often be misidentified by the conventional biochemical assays used by most medical laboratories. Since the start of COVID19 pandemic, there are many reports of C. auris outbreaks occurring in the hospitals and acute care facilities. Therefore, early and rapid diagnosis of C. auris infections is critical for controlling the outbreaks in any long-term care facilities.
C. auris has been classified as an “Urgent Threat” to public health by the U. S. Centers for Disease Control and Prevention for three main reasons: its multi-antifungal resistance, misidentification with standard laboratory methods and long-term survival on abiotic surfaces. The aim of this research topic is to understand the biology, pathogenesis, host interaction and mechanisms of antifungal resistance of C. auris. Furthermore, it aims to deliver information about the development of new tools and therapeutics to combat C. auris infections.
We welcome submissions of original research articles, reviews, mini-reviews and brief research reports in this research topic on C. auris that include but are not limited to the specific themes listed below:
• New tools and methods for rapid identification and accurate detection
• Development of new antifungals
• Emergence and molecular mechanism of antifungal resistance
• New methods for detecting of antifungal resistance
• Impact of steroid and antifungal usage in the hospitals
• Strategies for controlling antifungal resistance
Candida auris, a multidrug resistant fungal pathogen, which was first identified a decade ago, has been reported in many countries and continents globally. Since then, it has been associated with many outbreaks in hospitals and nursing homes as it can spread easily between patients. Furthermore, C. auris can persist for weeks on inanimate surfaces and medical equipment largely due to its limited sensitivity to non-sporicidal disinfectants. It can often be misidentified by the conventional biochemical assays used by most medical laboratories. Since the start of COVID19 pandemic, there are many reports of C. auris outbreaks occurring in the hospitals and acute care facilities. Therefore, early and rapid diagnosis of C. auris infections is critical for controlling the outbreaks in any long-term care facilities.
C. auris has been classified as an “Urgent Threat” to public health by the U. S. Centers for Disease Control and Prevention for three main reasons: its multi-antifungal resistance, misidentification with standard laboratory methods and long-term survival on abiotic surfaces. The aim of this research topic is to understand the biology, pathogenesis, host interaction and mechanisms of antifungal resistance of C. auris. Furthermore, it aims to deliver information about the development of new tools and therapeutics to combat C. auris infections.
We welcome submissions of original research articles, reviews, mini-reviews and brief research reports in this research topic on C. auris that include but are not limited to the specific themes listed below:
• New tools and methods for rapid identification and accurate detection
• Development of new antifungals
• Emergence and molecular mechanism of antifungal resistance
• New methods for detecting of antifungal resistance
• Impact of steroid and antifungal usage in the hospitals
• Strategies for controlling antifungal resistance