Animals carry a variety of pathogens, as they live in complex environments. Animal diseases not only pose a serious threat to animal health, especially rare and endangered wild animals but also cause serious zoonoses that threaten public health, such as papillomaviruses, CoVs, avian influenza, and others. In addition, due to the habits of wildlife migration, animals and birds are important disease spreaders, as they can transmit many zoonotic diseases across regions, country borders, intercontinental, and globally. Meanwhile, many mosquitoes and ticks carried by animals are also important vectors of diseases (vector-borne diseases), facilitating disease spread and causing huge economic loss to poultry and livestock, and bringing major public health problems to human beings.
Spillover of pathogens from wildlife to domestic animals or to humans can lead to the rapid evolution of the pathogen. Under the immune stress in new hosts, a high mutation and gene recombination rate play an essential role in the evolution of viruses, which is the leading cause of genetic diversity. Pathogens can evolve and acquire new biological properties which may pose a serious threat to the health of domestic animals and humans. Transmission of these host-adapted viruses to new species is uncommon. Some viruses are considered host-restricted. Host restriction is attributed to several factors, including lower viral fitness in the novel host, intrinsic antiviral defense mechanisms, and/or limited contact for transmission between different host species. However, in rare cases, the cross-species transmission may also occur and studies have indicated that cross-species transmission has also played an essential role in their evolution.
Pathogens carried by wild animals and birds are not only transmitted across proximal hosts but can also spread over wide ranges geographically via wildlife migration. Understanding the risks of wildlife-borne zoonotic diseases is necessary to increase awareness and facilitate the application of preventive and control measures to reduce disease spread.
This Research Topic will focus on animal-borne and vector-borne infectious diseases, including viral diseases, bacterial diseases, and other zoonotic diseases. The aim of this Research Topic is to study Zoonotic Diseases Originating from Animal: Emergence/Re-emergence, cross-species transmission, Evolution, Prevalence, and Pathogenesis in humans, Mosquitoes, Dogs, Cattle, and Pigs. We welcome manuscripts from the following subtopics:
- Vector-borne diseases
- Migration of wildlife and dispersal of disease
- The genetic evolution of the virus
- Pathogenic and transmission research
- Pathogenesis and virus-host interactions
- Host immune response
Animals carry a variety of pathogens, as they live in complex environments. Animal diseases not only pose a serious threat to animal health, especially rare and endangered wild animals but also cause serious zoonoses that threaten public health, such as papillomaviruses, CoVs, avian influenza, and others. In addition, due to the habits of wildlife migration, animals and birds are important disease spreaders, as they can transmit many zoonotic diseases across regions, country borders, intercontinental, and globally. Meanwhile, many mosquitoes and ticks carried by animals are also important vectors of diseases (vector-borne diseases), facilitating disease spread and causing huge economic loss to poultry and livestock, and bringing major public health problems to human beings.
Spillover of pathogens from wildlife to domestic animals or to humans can lead to the rapid evolution of the pathogen. Under the immune stress in new hosts, a high mutation and gene recombination rate play an essential role in the evolution of viruses, which is the leading cause of genetic diversity. Pathogens can evolve and acquire new biological properties which may pose a serious threat to the health of domestic animals and humans. Transmission of these host-adapted viruses to new species is uncommon. Some viruses are considered host-restricted. Host restriction is attributed to several factors, including lower viral fitness in the novel host, intrinsic antiviral defense mechanisms, and/or limited contact for transmission between different host species. However, in rare cases, the cross-species transmission may also occur and studies have indicated that cross-species transmission has also played an essential role in their evolution.
Pathogens carried by wild animals and birds are not only transmitted across proximal hosts but can also spread over wide ranges geographically via wildlife migration. Understanding the risks of wildlife-borne zoonotic diseases is necessary to increase awareness and facilitate the application of preventive and control measures to reduce disease spread.
This Research Topic will focus on animal-borne and vector-borne infectious diseases, including viral diseases, bacterial diseases, and other zoonotic diseases. The aim of this Research Topic is to study Zoonotic Diseases Originating from Animal: Emergence/Re-emergence, cross-species transmission, Evolution, Prevalence, and Pathogenesis in humans, Mosquitoes, Dogs, Cattle, and Pigs. We welcome manuscripts from the following subtopics:
- Vector-borne diseases
- Migration of wildlife and dispersal of disease
- The genetic evolution of the virus
- Pathogenic and transmission research
- Pathogenesis and virus-host interactions
- Host immune response