The eye is often times referred to as the ”window to the soul”. This is relevant to the practice of medicine as many systemic disorders can present with eye manifestations that can be detected by routine ophthalmic examination and the findings used to help physicians in the diagnosis and management of an individual patient. Conditions with potential eye manifestations include infections, metabolic disorders, auto-immune diseases, and exposure, to name a few. With respect to the latter, various toxicological exposures, whether environmental or clinical, can manifest with eye findings. Some associations are well characterized, such as crystalline retinal deposits that can occur with prolonged tamoxifen use, while others are less well described or understood.
In this special issue, we aim to highlight toxicological exposures that associate with eye manifestations, either directly or indirectly. We are interested in examining environmental exposures whose effect on the eye has not been well studied, such as toxic exposures during military service or in the setting of a natural disasters (e.g. fires). This environmental exposure can also be attributed to indoors, and the exposure to chemicals such as cleaning and cooking products. In addition, we wish to better define eye manifestations in the setting of clinical exposures, such as corneal abnormalities that can be seen with chemotherapeutic agents. For both topics, we welcome studies that forward understanding of mechanisms that underlie the noted human associations, whether through in vitro or animal in vivo models. These data will forward the field as a better understanding of links between toxic exposures and eye manifestations will allow for precision based diagnosis and management approaches that can be applied to an individual patient.
? Examine environmental exposures whose effect on the eye has not been well studied, such as toxic exposures during military service or in the setting of a natural disasters (e.g. fires).
? Better define eye manifestations that occur in the setting of clinical exposures, such as corneal abnormalities that can be seen with chemotherapeutic agents
? In vitro or in vivo animal studies that examine mechanisms that underlie the noted human associations between toxicologic exposures and eye diseases.
The eye is often times referred to as the ”window to the soul”. This is relevant to the practice of medicine as many systemic disorders can present with eye manifestations that can be detected by routine ophthalmic examination and the findings used to help physicians in the diagnosis and management of an individual patient. Conditions with potential eye manifestations include infections, metabolic disorders, auto-immune diseases, and exposure, to name a few. With respect to the latter, various toxicological exposures, whether environmental or clinical, can manifest with eye findings. Some associations are well characterized, such as crystalline retinal deposits that can occur with prolonged tamoxifen use, while others are less well described or understood.
In this special issue, we aim to highlight toxicological exposures that associate with eye manifestations, either directly or indirectly. We are interested in examining environmental exposures whose effect on the eye has not been well studied, such as toxic exposures during military service or in the setting of a natural disasters (e.g. fires). This environmental exposure can also be attributed to indoors, and the exposure to chemicals such as cleaning and cooking products. In addition, we wish to better define eye manifestations in the setting of clinical exposures, such as corneal abnormalities that can be seen with chemotherapeutic agents. For both topics, we welcome studies that forward understanding of mechanisms that underlie the noted human associations, whether through in vitro or animal in vivo models. These data will forward the field as a better understanding of links between toxic exposures and eye manifestations will allow for precision based diagnosis and management approaches that can be applied to an individual patient.
? Examine environmental exposures whose effect on the eye has not been well studied, such as toxic exposures during military service or in the setting of a natural disasters (e.g. fires).
? Better define eye manifestations that occur in the setting of clinical exposures, such as corneal abnormalities that can be seen with chemotherapeutic agents
? In vitro or in vivo animal studies that examine mechanisms that underlie the noted human associations between toxicologic exposures and eye diseases.
