Bioactive Soft Materials and Application

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About this Research Topic

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Background

Soft materials including gels, soft polymer composites, liquid crystals, polyelectrolyte multilayer films, etc., have been widely applied in biological and medical applications. The development of soft materials featuring adaptiveness to the biological environment, that can trigger and or/direct desirable cellular and tissue responses, or control interactions with microbiological species, and have biomimetic mechanical properties are highly demanded in regenerative medicine. These demands require the emerge of new conceptions and technologies to design both new materials and processes as well as the in-depth investigation at molecular level to better understand cell-materials, tissue-materials interactions and the biological response of human body. With the development of materials science, biotechnology and medical science, the intersection and integration of multi disciplines appears to be a promising way to develop appealing materials and promote their applications in basic, clinical and translation research.

Over the past few decades, the field of soft materials has been evolving very rapidly, because of their widespread applications, ranging from biomedical devices, tissue engineering, flexible displays to soft robots. A large number of new materials, in terms of bioactive gels, biomimetic surface coatings, soft polymer composites, etc., have been developed to be applied in the area of tissue repair and regenerative medicine. However, the application of the developed materials is often limited by various factors, such as the undesired biological responses upon contact with cells, and/or tissues and organs of living body, the failed matching and integration within the surrounding tissue, and the poor ability to induce and/or direct new tissue formation. This research topic aims to provide a platform for joint communication, discussion and inspiration among basic and clinical researches and developers from different disciplines to facilitate knowledge exchange and translation. The focus of this research topic will address the develop and application of bioactive soft materials in biomedical area.

The general topics of this research topic (not limited) are:
1. Research on the entire range of bioactive soft materials that have been specifically and functionally engineered or designed in term of either their topology, physical form, or dimensions.
2.Bioactive gels, bioactive soft polymers and/or composites, bioactive multilayer coatings, liquid crystals, etc., that for use as implants, cell/gene/drug carriers, tissue engineering scaffolds, imaging and sensing devices, or other applications in the biomedical area;
3. Synthesis and characterization of new soft materials with biological activity
4. Biological aspects of soft materials

Both review articles and research articles are welcomed.

Keywords: bioactive polymers and gels, surface coatings, bioactive films, interfaces and interactions, biological aspects of materials and interfaces, biomedical

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