Novel Therapeutic Targets for Lower Urinary Tract Symptoms

About this Research Topic

Background

Lower urinary tract symptoms (LUTS) affect millions of patients around the world, resulting in poor quality of life and enormous economic burden. LUTS can be caused by a broad spectrum of diseases, such as urinary tract infection, prostatitis, benign prostate hyperplasia, urethral stricture, neurogenic bladder, etc. Since LUTS involve different organs and neural pathways, the underlying mechanisms are complex and not fully elucidated. Furthermore, although there are various therapies for LUTS including oral medications, bladder instillation/injection, electrical stimulation, their overall effectiveness is unsatisfactory.

This Research Topic, therefore, focuses on the novel therapeutic targets for LUTS, including both basic studies and clinical trials. Novel treatments such as stem cell and gene therapy are encouraged for submission. This collection will provide a strong basis for the treatment of LUTS in the clinical practice.

The specific themes authors are encouraged to cover include, but are not limited to:
- Basic and animal studies of novel therapeutic targets for LUTS and underlying mechanisms
- High quality clinical trials for novel medications for LUTS
- Basic or clinical studies of stem cells/cytokines/exosomes to treat LUTS
- Basic and translational studies of gene therapy to treat LUTS
- Regenerative medicine in lower urinary tract for future therapy

Keywords: Therapeutic Targets, Lower Urinary Tract Symptoms, Regenerative Medicine, Gene Therapy

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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