Colorectal cancer is a disease involving multiple risk factors, including genetic, lifestyle, and environmental risk factors. According to statistics from the International Center for Research on Cancer of the World Health Organization, the incidence of colorectal cancer ranks third among all malignant tumors and the mortality rate ranks fourth. Numerous studies have shown that the gut microbiota played an important role in the occurrence and the development of colorectal cancer. Exploring the symbiotic effect between the gut microbiota and the digestive tract and the relationship between the gut microbiota and the pathogenesis of colorectal cancer based on the microbiota-metabolism-immune microenvironment will provide new strategies for the prevention and treatment of colorectal cancer.
Studies have proven the effect of drugs on the regulation of the balance of the intestinal micro-ecological system. It is characterized by comprehensive regulation of multiple pathways, multiple targets, and multiple effects, and has great potential in the prevention and treatment of gastrointestinal diseases, especially colorectal cancer. Importantly, some of them could improve the efficacy of chemotherapy, radiotherapy, and immunotherapy for colorectal cancer. Exploring the relationship between gut microbiota and the pathogenesis and therapeutic methods of colorectal cancer based on the metabolic-immune microenvironment will provide a new strategy for the prevention and treatment of colorectal cancer.
For this Research Topic, we aim to bring together recent advances on the effect of gut microbiota on the development of colorectal cancer and as strategies for the treatment of colorectal cancer. Studies on the regulatory effect and mechanisms of traditional Chinese medicine on the disturbance of gut microbes are also welcome. Potential topics of interest include but are not limited to the following:
• The effect of gut microbiota on the development of colorectal cancer
• The relationship between gut microbiota and chemotherapy resistance in colorectal cancer
• The effect of gut microbiota on the immunotherapy of colorectal cancer
• The potential role of gut microbiota in the TCM treatment of colorectal cancer
Colorectal cancer is a disease involving multiple risk factors, including genetic, lifestyle, and environmental risk factors. According to statistics from the International Center for Research on Cancer of the World Health Organization, the incidence of colorectal cancer ranks third among all malignant tumors and the mortality rate ranks fourth. Numerous studies have shown that the gut microbiota played an important role in the occurrence and the development of colorectal cancer. Exploring the symbiotic effect between the gut microbiota and the digestive tract and the relationship between the gut microbiota and the pathogenesis of colorectal cancer based on the microbiota-metabolism-immune microenvironment will provide new strategies for the prevention and treatment of colorectal cancer.
Studies have proven the effect of drugs on the regulation of the balance of the intestinal micro-ecological system. It is characterized by comprehensive regulation of multiple pathways, multiple targets, and multiple effects, and has great potential in the prevention and treatment of gastrointestinal diseases, especially colorectal cancer. Importantly, some of them could improve the efficacy of chemotherapy, radiotherapy, and immunotherapy for colorectal cancer. Exploring the relationship between gut microbiota and the pathogenesis and therapeutic methods of colorectal cancer based on the metabolic-immune microenvironment will provide a new strategy for the prevention and treatment of colorectal cancer.
For this Research Topic, we aim to bring together recent advances on the effect of gut microbiota on the development of colorectal cancer and as strategies for the treatment of colorectal cancer. Studies on the regulatory effect and mechanisms of traditional Chinese medicine on the disturbance of gut microbes are also welcome. Potential topics of interest include but are not limited to the following:
• The effect of gut microbiota on the development of colorectal cancer
• The relationship between gut microbiota and chemotherapy resistance in colorectal cancer
• The effect of gut microbiota on the immunotherapy of colorectal cancer
• The potential role of gut microbiota in the TCM treatment of colorectal cancer