Chronic pain (CP) is a high prevalent social issue that negatively impacts quality of life of affected individuals. We know that central and peripheral mechanisms are involved in the pain chronification process. Also, different types of chronic pain, such as arthritis, migraine, and fibromyalgia, might not share the same mechanisms. It is important to know that our understand of the mechanisms and risk factors underlying the development of chronic pain remains limited. These insights are essential to manage this condition in the clinical context and for the development of new preventive and therapeutic approaches, both pharmacological and non-pharmacological.
The goal of this Research Topic is to bring together a collection of papers that shed light on the mechanisms of chronic pain development. These insights will help to better understanding chronic pain and establish better clinical interventions and, more importantly, a path to prevent this condition.
We welcome the submission of manuscripts including, but not limited to, the following topics:
• Insights from animal models evidencing possible mechanisms underlying the development of the chronic pain:
- Models of neuropathic pain (e.g., nerve injury)
- Models of inflammatory pain and arthritis
- Models of dysfunctional pain (e.g., migraine)
• Insights from clinical trials evidencing behaviors and conditions that contributed to the chronic pain development.
• The role of the peripheral and/or central nervous system in the development of chronic pain.
Chronic pain (CP) is a high prevalent social issue that negatively impacts quality of life of affected individuals. We know that central and peripheral mechanisms are involved in the pain chronification process. Also, different types of chronic pain, such as arthritis, migraine, and fibromyalgia, might not share the same mechanisms. It is important to know that our understand of the mechanisms and risk factors underlying the development of chronic pain remains limited. These insights are essential to manage this condition in the clinical context and for the development of new preventive and therapeutic approaches, both pharmacological and non-pharmacological.
The goal of this Research Topic is to bring together a collection of papers that shed light on the mechanisms of chronic pain development. These insights will help to better understanding chronic pain and establish better clinical interventions and, more importantly, a path to prevent this condition.
We welcome the submission of manuscripts including, but not limited to, the following topics:
• Insights from animal models evidencing possible mechanisms underlying the development of the chronic pain:
- Models of neuropathic pain (e.g., nerve injury)
- Models of inflammatory pain and arthritis
- Models of dysfunctional pain (e.g., migraine)
• Insights from clinical trials evidencing behaviors and conditions that contributed to the chronic pain development.
• The role of the peripheral and/or central nervous system in the development of chronic pain.