Cancer is considered to be the second major cause of mortality worldwide and the further development of drugs and treatments is needed to increase the survival rates of the affected population. Scientists and researchers are constantly searching for new and improved methods to deal with immuno-oncological challenges and chemoresistance. Diet and lifestyle habits are responsible for evolving human microbiota within the host throughout their life, and they also play a critical role in drug metabolism. These factors contribute to why variation in gut microbiota resulted in inter-individual differences and altered responses toward chemotherapy, including drug induced efficacy and toxicity. Supplementation of probiotics restores responses against anticancer drugs, enhance immunity while reduces inflammations. Human body homeostasis is affected by gut microbiota and it has been widely observed that maintenance of healthy gut may prevent diseases along with amelioration of pathological conditions by secreting microbial metabolites, short chain fatty acid, lactic acid and much more. According to the World Health Organization (WHO) when administered in adequate amounts probiotics may confer a health benefit on the host. There are several strategies to deal with immuno-oncological challenges for cancer patients by using probiotics and these are under clinical trials.
Scientists are constantly searching for new drugs to deal with immuno-oncological challenges and chemoresistance. At present it is considered that in spite of follow up and effective drug targets, chemoresistance still takes place and is major cause of mortality and drug ineffectiveness. In this Research Topic we will be introducing novel strategies including probiotics to avoid drug resistance and result in an improved drug metabolism. By this adjuvant therapy, or intake of reported probiotics during chemotherapy, we will ensure that how to deal with immuno-oncological challenges faced by the clinicians.
? Probiotics as adjuvant therapy.
? Probiotics role in metabolism during chemotherapy.
? Clinical trial based studies of probiotics in oncology.
? Combination therapy with probiotics, along with Photomedicine.
? Inhibition of drug resistance by probiotics.
Cancer is considered to be the second major cause of mortality worldwide and the further development of drugs and treatments is needed to increase the survival rates of the affected population. Scientists and researchers are constantly searching for new and improved methods to deal with immuno-oncological challenges and chemoresistance. Diet and lifestyle habits are responsible for evolving human microbiota within the host throughout their life, and they also play a critical role in drug metabolism. These factors contribute to why variation in gut microbiota resulted in inter-individual differences and altered responses toward chemotherapy, including drug induced efficacy and toxicity. Supplementation of probiotics restores responses against anticancer drugs, enhance immunity while reduces inflammations. Human body homeostasis is affected by gut microbiota and it has been widely observed that maintenance of healthy gut may prevent diseases along with amelioration of pathological conditions by secreting microbial metabolites, short chain fatty acid, lactic acid and much more. According to the World Health Organization (WHO) when administered in adequate amounts probiotics may confer a health benefit on the host. There are several strategies to deal with immuno-oncological challenges for cancer patients by using probiotics and these are under clinical trials.
Scientists are constantly searching for new drugs to deal with immuno-oncological challenges and chemoresistance. At present it is considered that in spite of follow up and effective drug targets, chemoresistance still takes place and is major cause of mortality and drug ineffectiveness. In this Research Topic we will be introducing novel strategies including probiotics to avoid drug resistance and result in an improved drug metabolism. By this adjuvant therapy, or intake of reported probiotics during chemotherapy, we will ensure that how to deal with immuno-oncological challenges faced by the clinicians.
? Probiotics as adjuvant therapy.
? Probiotics role in metabolism during chemotherapy.
? Clinical trial based studies of probiotics in oncology.
? Combination therapy with probiotics, along with Photomedicine.
? Inhibition of drug resistance by probiotics.
