Host-pathogen interaction in cestodes infection

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About this Research Topic

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Background

Cestoda is a class in the phylum of platyhelminths, which consists of flat worms, whose body contains many segments. The cestode parasite life cycle progresses between two hosts and the larval and adult worm will cycle between species. The cestode class consists of parasites Taenia solium, Taenia saginata, Taenia multiceps, Diphyllobotrium lattum, Hymenolepis nana, Echinococcus granulosus, and Echinococcus multilocularis. Many cestode infections are asymptomatic, but the larval infection in the definitive and intermediate host is the major reason for morbidity and economic losses. Most specifically, Taenia solium and Taenia saginata cause a loss of millions of dollars in the livestock industries every year. One of the serious health issues associated with cestode infection is neurocysticercosis, caused by a Taenia solium larval infection in the human central nervous system. Neurocysticercosis is therefore the prime cause of late-stage seizures in the population in many of the Taenia solium infection-endemic countries. Based on a recent World Health Organization (WHO) report, 370000 people are affected due to late-stage seizures caused by cysticercal infections and more than 25000 deaths due to neurocysticercosis infection s annually .

Due to a lack of understanding of host-pathogen interaction in cestode infections, millions of dollars are lost in in meat industries every year. The world health organization describes Taenia infections as a neglected tropical disease due to the severity of health issues associated with Taenia infections. Therefore, this Research Topic aims to highlight current research investigating host-pathogen interactions in cestode infections. We invite researchers to submit articles of any type (Original Research, Review, Methods, Perspective, Mini-Review, Opinion) on but not limited to the following themes

• epidemiology of cestode infection
• diagnosis of cestode infection
• experimental models to understand cestode infection
• host immunity against cestode infection
• parasite evasion against immune attack

Keywords: cestode, parasite, infection, host-pathogen

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