The immune system can be highly sensitive to the stimuli provided by physical activity. In response, it can produce adaptations, modulating the immunological scenario in an acute or chronic way depending on the structure of the exercise protocol (intensity, volume, duration, rest time and type of pause). In this context, it is believed that different physical activity protocols, applied to several chronic diseases, are able to modulate the immunological profile and also the metabolism of immune cells. Thus, understanding the effects of different types of physical exercise on immune and immunometabolic responses in physiological conditions and in chronic diseases is of paramount importance for the scientific community.
Evidence indicates that physical activity changes the inflammatory profile and this is clearly observed by the reduction of pro-inflammatory cytokines levels and other key factors. In addition, physical exercise also exerts a strong influence on the metabolism of immune cells. Upon inflammatory stimulation, immune cells, such as macrophages and effector T cells require aerobic glycolysis. On the other hand, physical exercise promotes the oxidative metabolism which drives a switch towards an anti-inflammatory phenotype, promoting the buddy's homeostasis. Given the context described, the research topic objective is to elucidate and present how different physical exercise protocols can modulate immune system and immunometabolic responses in physiological conditions and in chronic diseases.
We highly encourage the author to submit original research article that illustrate mechanistically the interaction between physical exercise and the modulation of immune responses through changes in metabolism of immune cells in physiological and/or in chronic diseases context. Special attention will be also given to Systematic Reviews, Reviews and Mini-reviews focused on some of the topics described:
- Immune cells metabolism in different physical exercise protocols in the physiological and/or in chronic diseases context.
- Immune modulation induced by different physical exercise protocols in physiological conditions and/or chronic diseases.
- Immune cells metabolism in different physical exercise protocols in the physiological and/or in chronic diseases context.
- Physical exercise in viral infection.
- Physical exercise and vaccine efficacy.
The immune system can be highly sensitive to the stimuli provided by physical activity. In response, it can produce adaptations, modulating the immunological scenario in an acute or chronic way depending on the structure of the exercise protocol (intensity, volume, duration, rest time and type of pause). In this context, it is believed that different physical activity protocols, applied to several chronic diseases, are able to modulate the immunological profile and also the metabolism of immune cells. Thus, understanding the effects of different types of physical exercise on immune and immunometabolic responses in physiological conditions and in chronic diseases is of paramount importance for the scientific community.
Evidence indicates that physical activity changes the inflammatory profile and this is clearly observed by the reduction of pro-inflammatory cytokines levels and other key factors. In addition, physical exercise also exerts a strong influence on the metabolism of immune cells. Upon inflammatory stimulation, immune cells, such as macrophages and effector T cells require aerobic glycolysis. On the other hand, physical exercise promotes the oxidative metabolism which drives a switch towards an anti-inflammatory phenotype, promoting the buddy's homeostasis. Given the context described, the research topic objective is to elucidate and present how different physical exercise protocols can modulate immune system and immunometabolic responses in physiological conditions and in chronic diseases.
We highly encourage the author to submit original research article that illustrate mechanistically the interaction between physical exercise and the modulation of immune responses through changes in metabolism of immune cells in physiological and/or in chronic diseases context. Special attention will be also given to Systematic Reviews, Reviews and Mini-reviews focused on some of the topics described:
- Immune cells metabolism in different physical exercise protocols in the physiological and/or in chronic diseases context.
- Immune modulation induced by different physical exercise protocols in physiological conditions and/or chronic diseases.
- Immune cells metabolism in different physical exercise protocols in the physiological and/or in chronic diseases context.
- Physical exercise in viral infection.
- Physical exercise and vaccine efficacy.
