Helicobacter pylori is a pathogen that attacks and infects the lining of stomach and the duodenum leading to redness and inflammation. H. pylori infection is one of the common known cause for acute and chronic gastroduodenal ulcers. Another common manifestation of this infection is gastritis. There are also numerous studies that suggest possible connection between H. pylori infection and gastric cancer. These spiral shaped bacteria are capable of thriving in and manipulating the harsh acidic conditions of the stomach. The infection is generally treated with common antibiotics such clarithromycin, amoxicillin and tetracycline. However, resistance to these drugs have widely been observed complicating the treatment strategies.
There are continuous and ongoing efforts in understanding the structural features and mode of action of these pathogens vital in driving scientific discovery towards prevention and treatment strategies against these infections. Through this research topic we aim to explore the scientific gaps associated with our understanding of H. pylori pathogen and its importance to design better drug and treatment modalities.
The current Research Topic aims to highlight the latest scientific findings on these pathogens in the following areas:
1. Mode of transmission between the hosts.
2. Pathogenesis and resistance mechanisms developed by the species.
3. Host-pathogen interaction and immune evasion mechanisms.
4. Prevention strategies to stem the infection.
5. Novel treatment strategies against the infection.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Helicobacter pylori is a pathogen that attacks and infects the lining of stomach and the duodenum leading to redness and inflammation. H. pylori infection is one of the common known cause for acute and chronic gastroduodenal ulcers. Another common manifestation of this infection is gastritis. There are also numerous studies that suggest possible connection between H. pylori infection and gastric cancer. These spiral shaped bacteria are capable of thriving in and manipulating the harsh acidic conditions of the stomach. The infection is generally treated with common antibiotics such clarithromycin, amoxicillin and tetracycline. However, resistance to these drugs have widely been observed complicating the treatment strategies.
There are continuous and ongoing efforts in understanding the structural features and mode of action of these pathogens vital in driving scientific discovery towards prevention and treatment strategies against these infections. Through this research topic we aim to explore the scientific gaps associated with our understanding of H. pylori pathogen and its importance to design better drug and treatment modalities.
The current Research Topic aims to highlight the latest scientific findings on these pathogens in the following areas:
1. Mode of transmission between the hosts.
2. Pathogenesis and resistance mechanisms developed by the species.
3. Host-pathogen interaction and immune evasion mechanisms.
4. Prevention strategies to stem the infection.
5. Novel treatment strategies against the infection.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.