Degenerative orthopedic conditions are the gradual loss of the structure and function of cartilage and bone, which are mainly manifested in joints, spine and bone quality, such as osteoarthritis, osteoporosis, lumbar intervertebral disc herniation, cervical spondylosis, spinal stenosis, degenerative spondylolisthesis, bone hyperplasia and painful heel. Currently, 10% of medical practices worldwide are related to degenerative orthopedic conditions. Although there have been significant improvements in the treatment of degenerative orthopedic conditions, including drugs, surgical techniques and perioperative care, there are still various deficiencies in these treatments. New therapeutic strategies are also emerging, including improvements in preoperative assessment to better estimate a patient's individual risk, and improvements in imaging and virtual planning to surgically eradicate the site of the lesion with greater precision. A large number of experimental studies have focused on the etiology, pathogenesis, animal models and treatment methods of orthopedic degenerative conditions, providing the possibility to discover new therapeutic methods.
The purpose of this topic is to provide cutting-edge research data from clinical and experimental studies to improve treatment outcomes for degenerative orthopedic conditions. We would like to invite the authors to share their thoughts, patient selection criteria and experiences, new perioperative measures, including preoperative conditions and postoperative rehabilitation, surgical strategies and techniques, and required institutional settings.
The scope of this specific collection covers clinical trials, narrative reviews, systematic reviews, meta-analyses, case reports, and experimental animal studies. We welcome contributions focus on the following:
• Novel therapeutic techniques on degenerative orthopedic conditions;
• New rehabilitation methods on degenerative joint and bone diseases;
• Novel degeneration or ageing related mechanisms;
• New therapeutic targets development in bone and joint diseases;
• Novel biomarkers in the pathogenesis of degenerative bone and joint disease;
• New regenerative biomaterials in degenerative bone and joint diseases.
Degenerative orthopedic conditions are the gradual loss of the structure and function of cartilage and bone, which are mainly manifested in joints, spine and bone quality, such as osteoarthritis, osteoporosis, lumbar intervertebral disc herniation, cervical spondylosis, spinal stenosis, degenerative spondylolisthesis, bone hyperplasia and painful heel. Currently, 10% of medical practices worldwide are related to degenerative orthopedic conditions. Although there have been significant improvements in the treatment of degenerative orthopedic conditions, including drugs, surgical techniques and perioperative care, there are still various deficiencies in these treatments. New therapeutic strategies are also emerging, including improvements in preoperative assessment to better estimate a patient's individual risk, and improvements in imaging and virtual planning to surgically eradicate the site of the lesion with greater precision. A large number of experimental studies have focused on the etiology, pathogenesis, animal models and treatment methods of orthopedic degenerative conditions, providing the possibility to discover new therapeutic methods.
The purpose of this topic is to provide cutting-edge research data from clinical and experimental studies to improve treatment outcomes for degenerative orthopedic conditions. We would like to invite the authors to share their thoughts, patient selection criteria and experiences, new perioperative measures, including preoperative conditions and postoperative rehabilitation, surgical strategies and techniques, and required institutional settings.
The scope of this specific collection covers clinical trials, narrative reviews, systematic reviews, meta-analyses, case reports, and experimental animal studies. We welcome contributions focus on the following:
• Novel therapeutic techniques on degenerative orthopedic conditions;
• New rehabilitation methods on degenerative joint and bone diseases;
• Novel degeneration or ageing related mechanisms;
• New therapeutic targets development in bone and joint diseases;
• Novel biomarkers in the pathogenesis of degenerative bone and joint disease;
• New regenerative biomaterials in degenerative bone and joint diseases.